Miranda-Massari Jorge R, González Michael J, Duconge Jorge, Allende-Vigo Myriam Z, Jiménez-Ramírez Francisco J, Hickey Steve, Vázquez Alex, Berdiel Miguel J, Cintrón Kenneth, Rodríguez-Gómez José R
P R Health Sci J. 2015 Mar;34(1):9-13.
A healthy physiology depends on a plethora of complex interdependent biochemical reactions. In order for these reactions to occur suitably, the enzymes and cofactors that regulate their flow must be present in the proper balance. The term metabolic correction is used to describe a biochemical-physiological process that improves cellular biochemistry as a means to an individual's achieving metabolic or physiological optimization. Part 2 discusses how metabolic correction, through the increase of cofactors, can supply unmet enzyme needs and compensate for nutritional deficiencies induced by improper nutritional intake or by the increased demand for nutrients caused by genetics, health conditions, medications, or physical or environmental stressors. Nutrient insufficiencies are causing an increase in morbidity and mortality, at great cost to our society. In summary, metabolic correction improves enzymatic function and satisfies the increasing demand for nutrients. Metabolic correction can have a significant impact on the reduction of morbidity and mortality and their financial cost to our society and contribute to improving health and well-being.
健康的生理机能依赖于大量复杂且相互依存的生化反应。为了使这些反应适当地发生,调节其进程的酶和辅助因子必须以适当的平衡存在。术语“代谢校正”用于描述一种生化生理过程,该过程改善细胞生化,作为个体实现代谢或生理优化的一种手段。第二部分讨论了代谢校正如何通过增加辅助因子来满足未得到满足的酶需求,并弥补因营养摄入不当或因遗传、健康状况、药物、身体或环境压力源导致的营养需求增加所引起的营养缺乏。营养不足正导致发病率和死亡率上升,给我们的社会带来巨大代价。总之,代谢校正改善酶功能并满足对营养素日益增长的需求。代谢校正可对降低发病率和死亡率及其给我们社会带来的经济成本产生重大影响,并有助于改善健康和福祉。