Miura Kei-Ichiro, Yoshida Masashi, Asahina Izumi
Assistant Professor, Department of Regenerative Oral Surgery, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan; Department of Oral Surgery, Imakiire General Hospital, Kagoshima, Japan.
Head, Department of Oral Surgery, Imakiire General Hospital, Kagoshima, Japan.
J Oral Maxillofac Surg. 2015 Jun;73(6):1050-7. doi: 10.1016/j.joms.2015.01.004. Epub 2015 Jan 20.
One of the most important purposes of secondary bone grafting of the alveolar cleft is to stabilize the maxillary alveolar arch with completion of the dental arch. We report a case of secondary bone grafting with simultaneous auto-tooth transplantation to the alveolar cleft, using particulate cancellous bone and marrow (PCBM) combined with platelet-rich plasma (PRP), which contains many growth factors. The patient was born with a bilateral cleft lip and left buccal-localized cleft alveolus. We performed bone grafting to the cleft using PCBM with PRP and transplantation of the supernumerary tooth under general anesthesia when the patient was aged 11 years, 10 months. The postoperative course was uneventful and without any complications. The orthodontic treatment was nearly complete 10 months after the operation. The transplanted tooth was stable, and a normal gingival contour was attained during the 2-year follow-up period. The case was successful in achieving a stable occlusal condition within a short period. We suggest secondary bone grafting with simultaneous auto-tooth transplantation as an option for alveolar cleft treatment.
牙槽嵴裂二期植骨的最重要目的之一是通过牙弓的完成来稳定上颌牙槽弓。我们报告一例牙槽嵴裂二期植骨同时自体牙移植的病例，使用颗粒状松质骨和骨髓（PCBM）并结合富含血小板血浆（PRP），PRP含有多种生长因子。该患者出生时患有双侧唇裂和左侧颊部局限性牙槽嵴裂。患者11岁10个月时，在全身麻醉下使用含PRP的PCBM对裂隙进行植骨，并移植多生牙。术后过程顺利，无任何并发症。术后10个月正畸治疗基本完成。在2年的随访期内，移植牙稳定，牙龈轮廓正常。该病例成功在短时间内实现了稳定的咬合状态。我们建议将牙槽嵴裂二期植骨同时自体牙移植作为牙槽嵴裂治疗的一种选择。
