Hepp Nancy Morris
U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, Office of Cosmetics and Colors, College Park, MD 20740, USA.
J AOAC Int. 2015 Jan-Feb;98(1):160-4. doi: 10.5740/jaoacint.13-284.
Specifications in the Code of Federal Regulations limit the levels of As, Pb, and Hg in most certifiable color additives, and some have additional specification limits for Cr and Mn. A new ICP/MS method was developed and validated for the quantitative determination of these elements in various certifiable color additives. One dissolution and two microwave-assisted digestion sample preparation procedures were optimized to address initial low Hg and enhanced As recoveries. Results using the three sample preparation procedures were generally equivalent for all of the elements determined. LOQ values were 0.3 mg/kg for As, 0.7 mg/kg for Cr, 0.4 mg/kg for Pb, 0.7 mg/kg for Mn, and 0.1 mg/kg for Hg.
《联邦法规法典》中的规范限制了大多数可认证色素添加剂中砷、铅和汞的含量，有些还对铬和锰有额外的规范限制。开发并验证了一种新的电感耦合等离子体质谱法（ICP/MS），用于定量测定各种可认证色素添加剂中的这些元素。优化了一种溶解和两种微波辅助消解样品制备程序，以解决初始汞含量低和提高砷回收率的问题。使用这三种样品制备程序得到的结果对于所有测定元素总体相当。砷的定量限（LOQ）值为0.3毫克/千克，铬为0.7毫克/千克，铅为0.4毫克/千克，锰为0.7毫克/千克，汞为0.1毫克/千克。
