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一名恶性淋巴瘤患者及健康个体体内的抗 A 样和抗 B 样冷凝集素

Anti-A-like and anti-B-like cold auto-hemagglutinins in a patient with malignant lymphoma and healthy individuals.

作者信息

Itoh Y, Matsuzawa S

出版信息

Nihon Hoigaku Zasshi. 1989 Aug;43(4):332-6.

PMID:2585822
Abstract

A cold auto-hemagglutinin with anti-B-like specificity was found in the serum of a group B patient with malignant lymphoma. The auto-hemagglutinin reacted only with B (adult) red cells and was inhibited by B secretor saliva. The appearance of this hemagglutinin in the patient's serum was transient. The presence of cold auto-hemagglutinins with anti-A-like and/or anti-B-like specificities was also demonstrated in sera from 15 (14.4%) of 104 group A1B healthy Japanese adults. The immunological features of these cold auto-hemagglutinins were similar to those of the anti-B-like hemagglutinin in the patient with malignant lymphoma.

摘要

在一名患有恶性淋巴瘤的B型血患者血清中发现了一种具有抗B样特异性的冷凝集素。这种自身凝集素仅与B(成人)红细胞发生反应,并被B分泌型唾液所抑制。该凝集素在患者血清中的出现是短暂的。在104名A1B型健康日本成年人中,有15名(14.4%)的血清中也检测到了具有抗A样和/或抗B样特异性的冷凝集素。这些冷凝集素的免疫学特征与恶性淋巴瘤患者体内抗B样凝集素的特征相似。

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