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[桡骨长轴断层扫描:一种用于铊-201心肌单光子发射计算机断层扫描的新重建算法]

[Radial long-axis tomography: a new reconstructing algorithm for thallium-201 myocardial SPECT].

作者信息

Ishida Y, Tani A, Morozumi R, Matsubara N, Hori M, Kitabatake A, Kamada T, Nakamura Y, Kozuka T, Kimura K

出版信息

Kaku Igaku. 1989 Oct;26(10):1267-77.

PMID:2585840
Abstract

The long-axis (L-A) tomograms of the heart in thallium-201 SPECT have been conventionally reconstructed as those parallel to the midventricular vertical or horizontal L-A plane. We developed a new algorithm for reconstructing the rotated L-A tomograms around the L-A to longitudinally observe thallium-201 myocardial distribution and to provide an optimal view of the cardiac apex. After determining the orientation of the L-A and reconstructing the short-axis (S-A) tomograms using standard techniques, the coordinates of the S-A planes were transformed to the polar coordinates whose origin is located at the position of the L-A in each plane. Then, "radial L-A tomograms", i.e. midventricular L-A planes oriented at the angle of every 6 degrees to the midventricular horizontal L-A plane, were reconstructed. Also, we developed a new technique for analyzing thallium-201 distribution of the L-A tomograms. For the basal 2/3 regions, two profiles which consist of the pixels with maximum count on the upper and lower myocardial portions of the lines (spaced at 1 pitch) vertically to the L-A were computed. For the remaining apical 1/3 regions, the semi-circumferential maximum-count profile from the values of 30 radii spaced at 6 degrees interval were computed. Based on these profiles, a 2D polar representation was then generated. From the study using a cardiac phantom with an apical small infarction, the usefulness of this new tomographic method for the detection of apical myocardial ischemia was demonstrated. The application to the exercise/redistribution studies in patients with effort angina indicated that radial long-axis tomography provides precise information about the longitudinal extent of perfusion defects, particularly in the apical regions.

摘要

传统上,铊-201单光子发射计算机断层扫描(SPECT)心脏长轴(L-A)断层图像被重建为与心室中部垂直或水平L-A平面平行的图像。我们开发了一种新算法,用于重建围绕L-A旋转的L-A断层图像,以便纵向观察铊-201心肌分布并提供心脏尖部的最佳视图。在确定L-A的方向并使用标准技术重建短轴(S-A)断层图像后,将S-A平面的坐标转换为极坐标,其原点位于每个平面中L-A的位置。然后,重建“径向L-A断层图像”,即与心室中部水平L-A平面成每6度角的心室中部L-A平面。此外,我们还开发了一种分析L-A断层图像铊-201分布的新技术。对于基底2/3区域,计算由垂直于L-A的线(间隔1个间距)的心肌上下部分上具有最大计数的像素组成的两个轮廓。对于其余的尖部1/3区域,计算从30个以6度间隔分布的半径值得到的半圆周最大计数轮廓。基于这些轮廓,然后生成二维极坐标表示。通过使用具有尖部小梗死的心脏模型的研究,证明了这种新断层扫描方法对检测尖部心肌缺血的有用性。将其应用于劳力性心绞痛患者的运动/再分布研究表明,径向长轴断层扫描提供了有关灌注缺损纵向范围的精确信息,特别是在尖部区域。

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