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药房报销数据与患者自我报告用于衡量避孕方法的持续使用情况。

Pharmacy claims data versus patient self-report to measure contraceptive method continuation.

作者信息

Triebwasser Jourdan E, Higgins Stephanie, Secura Gina M, Zhao Qiuhong, Peipert Jeffrey F

机构信息

Washington University in St. Louis School of Medicine Department of Obstetrics and Gynecology, Division of Clinical Research, 660 South Euclid Avenue Campus Box 8064, St. Louis, MO 63108, USA.

Washington University in St. Louis School of Medicine Department of Obstetrics and Gynecology, Division of Clinical Research, 660 South Euclid Avenue Campus Box 8064, St. Louis, MO 63108, USA.

出版信息

Contraception. 2015 Jul;92(1):26-30. doi: 10.1016/j.contraception.2015.03.016. Epub 2015 Apr 7.

Abstract

OBJECTIVE

To compare self-reported 12-month continuation of oral contraceptive pills (OCPs), patch, and ring versus continuation by pharmacy claims data.

STUDY DESIGN

Women in the Contraceptive CHOICE Project who chose OCPs, the patch, or the ring as their initial method were included. Continuation was assessed by periodic telephone survey and by obtaining prescription claims data. Continuation was defined as no gap of more than 30 days. Kaplan-Meier survival functions were used to estimate continuation rates and cumulative unintended pregnancy rates. Kappa statistic assessed the level of agreement between self-report and claims data.

RESULTS

We analyzed 1510 women who initiated use by 3 months and provided information on discontinuation. Of OCP users, 59% continued their method at 12 months by self-report versus 38% by pharmacy claims. Patch and ring users had self-reported/pharmacy continuation of 45%/28% and 57%/37%, respectively. Kappa coefficients and their 95% confidence intervals between the two measurements were 0.46 (0.40, 0.52), 0.54 (0.39, 0.68), and 0.54 (0.47, 0.61) for OCP, patch, and ring, respectively. Among women who self-reported continuation, unintended pregnancy rates were 0.4% in those who continued by pharmacy claims versus 4.9% in those who discontinued according to claims data.

CONCLUSION

Contraceptive continuation rates differ by self-report versus pharmacy claims with women overestimating their continuation by self-report.

IMPLICATIONS

This article directly compares contraception continuation rates by self-report and by pharmacy claims data. The study suggests that previously reported continuation rates from survey data overestimate specific method use.

摘要

目的

比较通过自我报告得出的口服避孕药(OCP)、避孕贴片和阴道避孕环的12个月持续使用情况与药房报销数据显示的持续使用情况。

研究设计

纳入避孕选择项目中最初选择OCP、避孕贴片或阴道避孕环作为避孕方法的女性。通过定期电话调查和获取处方报销数据来评估持续使用情况。持续使用定义为中断时间不超过30天。采用Kaplan-Meier生存函数来估计持续使用率和累积意外妊娠率。Kappa统计量用于评估自我报告与报销数据之间的一致性水平。

结果

我们分析了1510名在3个月内开始使用并提供了停药信息的女性。在OCP使用者中,自我报告显示12个月时59%的人持续使用该方法,而药房报销数据显示为38%。避孕贴片和阴道避孕环使用者自我报告/药房报销的持续使用率分别为45%/28%和57%/37%。OCP、避孕贴片和阴道避孕环两种测量方法之间的Kappa系数及其95%置信区间分别为0.46(0.40,0.52)、0.54(0.39,0.68)和0.54(0.47,0.61)。在自我报告持续使用的女性中,药房报销数据显示持续使用者的意外妊娠率为0.4%,而根据报销数据中断使用的女性意外妊娠率为4.9%。

结论

避孕持续使用率在自我报告和药房报销数据之间存在差异,女性自我报告高估了她们的持续使用率。

启示

本文直接比较了自我报告和药房报销数据得出的避孕持续使用率。该研究表明,先前调查数据报告的持续使用率高估了特定避孕方法的使用情况。

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Studying the use of oral contraception: a review of measurement approaches.研究口服避孕药的使用:测量方法综述。
J Womens Health (Larchmt). 2010 Dec;19(12):2203-10. doi: 10.1089/jwh.2010.1963. Epub 2010 Oct 30.
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Social desirability bias in family planning studies: a neglected problem.计划生育研究中的社会期望偏差:一个被忽视的问题。
Contraception. 2009 Aug;80(2):108-12. doi: 10.1016/j.contraception.2009.02.009. Epub 2009 Apr 22.

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