BLOODCENTER OF WISCONSIN.
Blood. 2015 Apr 9;125(15):2319-20. doi: 10.1182/blood-2015-02-629782.
In this issue of Blood, Rollin et al demonstrate that heparin-induced thrombocytopenia and thrombosis (HIT) patients homozygous for arginine (R) at position 131 in the immunoglobulin (Ig)G receptor FcγRIIA have a significantly higher incidence of thrombosis, and show that plasma IgG may play a key role in modulating the thrombotic process.
在本期《Blood》中，Rollin 等人表明，免疫球蛋白 (Ig)G 受体 FcγRIIA 位置 131 处精氨酸 (R) 为纯合子的肝素诱导的血小板减少症和血栓形成 (HIT) 患者，其血栓形成的发生率显著更高，并且表明血浆 IgG 可能在调节血栓形成过程中发挥关键作用。
