Mashimoto H, Kaku M, Araki J, Asai S, Takada T, Kubota H, Matsuo T, Ikeda T
Nihon Kyobu Shikkan Gakkai Zasshi. 1989 Sep;27(9):1087-91.
A 66 year-old male was admitted on October 31, 1987 because his chest X-ray film revealed a well-defined round shadow in the right inferior mediastinum. Chest CT showed a large homogenous mass in the right anterior mediastinum. The mass was identified as a cyst on echogram. Surgical removal of the cyst was done with right thoracotomy. The cyst was 15 cm in size and contained about 500 ml of grayish white fluid. Pathological examination showed a thymic cyst and no malignancy. Biochemical analysis of the cystic fluid revealed increased CEA value of 223.2 ng/dl in spite of normal CEA level in serum. CEA was demonstrated in the epithelium of the surface and Hassall's corpuscles by PAP stain. It is conceivable that this elevated CEA observed in the cystic fluid might be correlated with CEA-like antigens such as NCA, NFA and BGP.
一名66岁男性于1987年10月31日入院，因为其胸部X光片显示右下纵隔有一个边界清晰的圆形阴影。胸部CT显示右前纵隔有一个大的均匀肿块。在超声检查中该肿块被确定为囊肿。通过右胸切开术对囊肿进行了手术切除。囊肿大小为15厘米，含有约500毫升灰白色液体。病理检查显示为胸腺囊肿，无恶性病变。囊液的生化分析显示，尽管血清中癌胚抗原（CEA）水平正常，但囊液中CEA值升高至223.2纳克/分升。通过过氧化物酶抗过氧化物酶（PAP）染色在表面上皮和哈氏小体中发现了CEA。可以想象，在囊液中观察到的这种CEA升高可能与诸如非癌性抗原（NCA）、正常胎儿抗原（NFA）和嗜铬粒蛋白B（BGP）等CEA样抗原有关。
