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[前列腺腺癌外科治疗指南]

[Guideline of surgical treatment of prostatic adenocarcinoma].

作者信息

Nishiyama N, Nagakubo I, Moriguchi R, Ishiguro K, Horiba M, Izumitani M

出版信息

Nihon Hinyokika Gakkai Zasshi. 1989 Aug;80(8):1162-7. doi: 10.5980/jpnjurol1989.80.1162.

Abstract

Based on study of 274 cases of prostate cancer treated in our clinic, selection of patient for radical surgical treatment and choice of procedures were discussed. The radical surgical procedures experienced in our clinic were classified as 31 cases of radical prostatectomy, 4 cases of radical cystoprostatectomy and 7 cases of pelvic exenteration. The endocrine therapy was added to non curative cases postoperatively. In the radical prostatectomy group, the 5-year survival rate of patients with stage A and stage B prostatic adenocarcinoma were 100 and 93 per cent, respectively, and 5-year survival rate of patients who had stage C prostatic adenocarcinoma was 75 per cent. The 5-year survival rates of patients with stage C prostatic adenocarcinoma treated by radical cystoprostatectomy and pelvic exenteration were 50 per cent and 66 per cent, respectively. Cancer recurrence has not seen in the bladder in the patients with stage C prostatic adenocarcinoma treated by radical prostatectomy. Operation of urinary diversion had improved the quality of life. From this data, radical prostatectomy would be indicated for the treatment of patients with stage A, stage B and stage C prostatic adenocarcinoma.

摘要

基于对我院诊治的274例前列腺癌患者的研究,探讨了根治性手术治疗患者的选择及手术方式的选择。我院开展的根治性手术包括31例根治性前列腺切除术、4例根治性膀胱前列腺切除术和7例盆腔脏器清除术。对非根治性病例术后加用内分泌治疗。在根治性前列腺切除术组中,A期和B期前列腺腺癌患者的5年生存率分别为100%和93%,C期前列腺腺癌患者的5年生存率为75%。经根治性膀胱前列腺切除术和盆腔脏器清除术治疗的C期前列腺腺癌患者的5年生存率分别为50%和66%。接受根治性前列腺切除术治疗的C期前列腺腺癌患者膀胱未见癌复发。尿流改道术改善了生活质量。根据这些数据,根治性前列腺切除术适用于A期、B期和C期前列腺腺癌患者的治疗。

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