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单个椎体出现成骨细胞性和破骨细胞性转移——一种罕见的表现。

Osteoblastic and osteoclastic metastases in a single vertebra-a rare presentation.

作者信息

Chand Gian, Chhabra Ajay, Mangat Deepshikha, Grover Suparna

机构信息

Associate Professor, Department of Medicine, Government Medical College , Amritsar, India .

Assistant Professor, Department of Medicine, Government Medical College , Amritsar, India .

出版信息

J Clin Diagn Res. 2015 Feb;9(2):OD07-8. doi: 10.7860/JCDR/2015/11237.5543. Epub 2015 Feb 1.

Abstract

Malignancies may produce bony metastases which may be osteoclastic or osteoblastic. Vertebrae are a common site for bony metastases. Prostatic adenocarcinoma is an important source of vertebral metastases that are mainly osteoblastic in nature. As the osteoblastic metastases are developing there is an ongoing osteoclastic activity which is going on at the microscopic level. Presence of gross osteoblastic and osteoclastic lesions, in the same vertebra, have not been reported at the time of presentation. Here a rare case of vertebral metastases is being presented which shows osteoblastic and osteoclastic gross lesions in the same vertebra.

摘要

恶性肿瘤可产生骨转移瘤,其可为破骨性或成骨性。脊椎是骨转移瘤的常见部位。前列腺腺癌是椎体转移瘤的重要来源,其本质上主要是成骨性的。在成骨性转移瘤形成过程中,在微观层面存在持续的破骨细胞活性。在疾病呈现时,同一椎体出现明显的成骨和破骨病变尚未见报道。本文报告了一例罕见的椎体转移瘤病例,该病例在同一椎体上显示出明显的成骨和破骨病变。

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本文引用的文献

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Physiopathology of spine metastasis.脊柱转移瘤的病理生理学
Int J Surg Oncol. 2011;2011:107969. doi: 10.1155/2011/107969. Epub 2011 Aug 10.
6
Primary bone and metastatic tumors of the cervical spine.
Spine (Phila Pa 1976). 1998 Dec 15;23(24):2767-77. doi: 10.1097/00007632-199812150-00019.

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