Allhoff P G, Laaser U
Arbeitsgemeinschaft für interdisziplinäre Gesundheitsforschung, Leverkusen.
Klin Wochenschr. 1989 Nov 17;67(22):1147-51. doi: 10.1007/BF01726116.
In connection with a large population screening (N = 24317) in Bielefeld/Federal Republic of Germany a physicians inquiry has been carried out with a return of 55 out of 105 general practitioners or internists (52.4%), about 60% practicing already more than 10 years in Bielefeld. Only 42% of the answering physicians determine cholesterol in every new patient. Only 13% used own laboratory equipment, only 4% dry chemistry (almost indispensable for screening purposes). About 35% consider cholesterol lowering drug therapy to be necessary only beyond values of 300 mg/dl total cholesterol, the mean borderline value for the prescription of cholesterol lowering drugs was 265 mg/dl. Especially positions of shorter practice experience seemed to be sceptical taughts pharmacological means. The most utilized pharmacological preparations in Bielefeld correspond well with the "Arzneiverordnungs-Report '88". Side effects seem to be frequent as only three positions indicated that none of the patients under drug therapy had reported unwanted effects. Most physicians considered dietary therapy to be less effective than drug therapy. Almost all of them took means to increase the compliance of their patients, mainly (82%) through at least three monthly consultations. The prevalence of patients under cholesterol lowering dietary or pharmacologic therapy varied from 5 to 65% with the median of 17.5% which indicates a considerable underdetection of cases. However, physicians seem to be conscious about that as almost 80% hold more public information on cholesterol for desirable or (60%) very desirable.
在德国比勒费尔德进行的一项大规模人群筛查(N = 24317)中,对医生进行了调查,105名全科医生或内科医生中有55人回复(回复率为52.4%),约60%的医生在比勒费尔德执业已超过10年。只有42%的回复医生会在每位新患者中检测胆固醇。只有13%的医生使用自己的实验室设备,只有4%的医生使用干化学法(这对筛查目的几乎必不可少)。约35%的医生认为只有当总胆固醇值超过300mg/dl时才需要进行降胆固醇药物治疗,降胆固醇药物处方的平均临界值为265mg/dl。特别是执业经验较短的医生似乎对药物治疗手段持怀疑态度。比勒费尔德最常用的药物制剂与《1988年药品处方报告》相符。副作用似乎很常见,因为只有三个科室表示接受药物治疗的患者中没有人报告有不良反应。大多数医生认为饮食疗法不如药物疗法有效。几乎所有医生都采取措施提高患者的依从性,主要是(82%)通过至少每三个月进行一次咨询。接受降胆固醇饮食或药物治疗的患者患病率从5%到65%不等,中位数为17.5%,这表明病例检测存在相当大的不足。然而,医生们似乎意识到了这一点,因为近80%的医生认为提供更多关于胆固醇的公共信息是可取的或(60%)非常可取的。