Vartbaronov R A, Glod G D, Popov I G, Uglova N N, Sarycheva N N, Rolik I S
Kosm Biol Aviakosm Med. 1989 Aug-Sep;23(4):43-6.
Experiments of the series were carried out using 7 noninbred dogs. In the first series, the animals were exposed to + GZ acceleration of increasing value once or twice a week during 5 months. Each exposure continued until distinct cardiac arrhythmias were seen in ECG. Two weeks after the onset of exposure the dogs displayed hyponatremia and higher K-Na coefficient and two months later they showed hyperkalemia and hypermagnesemia which led to a 1.5 G increase of acceleration tolerance. In the second experimental series, the animals exhibited a beneficial effect of hypermagnesemia on circulation parameters and frequency of cardiac arrhythmias in response to a single + GZ exposure. These observations have demonstrated that electrolyte balance plays an important part in the development of adaptation to sustained acceleration.
该系列实验使用了7只非近亲繁殖的狗。在第一个系列实验中,动物在5个月内每周接受一次或两次逐渐增加的+ GZ加速度暴露。每次暴露持续到心电图中出现明显的心律失常。暴露开始两周后,狗出现低钠血症和较高的钾钠系数,两个月后出现高钾血症和高镁血症,这导致加速度耐受性增加了1.5 G。在第二个实验系列中,动物在单次+ GZ暴露后,高镁血症对循环参数和心律失常频率产生了有益影响。这些观察结果表明,电解质平衡在持续加速度适应的发展中起着重要作用。