Corwin H L, Sprague S M, DeLaria G A, Norusis M J
Department of Medicine, Rush Presbyterian-St. Luke's Medical Center, Chicago, Ill.
J Thorac Cardiovasc Surg. 1989 Dec;98(6):1107-12.
We performed a case-control study to identify risk factors for the development of acute renal failure after cardiac operations. Forty-two cases of acute renal failure were identified in a total of 572 patients who underwent cardiac operations. They were matched with a control population of patients having cardiac operations without acute renal failure. Discriminant analysis performed with preoperative variables revealed preoperative serum creatinine values, concurrent valve and bypass surgery, and age to be significant variables for identifying patients at risk for acute renal failure. The use of these three variables in a discriminant model correctly classified 77% of patients. The addition of intraoperative variables did not significantly improve the ability of the model to correctly classify patients. Acute renal failure was associated with a significant increase in the number of postoperative complications, mortality, and length of hospitalization and intensive care unit stay.
我们进行了一项病例对照研究，以确定心脏手术后发生急性肾衰竭的危险因素。在总共572例接受心脏手术的患者中，确定了42例急性肾衰竭病例。将他们与未发生急性肾衰竭的接受心脏手术的对照人群进行匹配。对术前变量进行判别分析显示，术前血清肌酐值、同期瓣膜和搭桥手术以及年龄是识别急性肾衰竭风险患者的重要变量。在判别模型中使用这三个变量可正确分类77%的患者。添加术中变量并未显著提高模型正确分类患者的能力。急性肾衰竭与术后并发症数量、死亡率以及住院时间和重症监护病房停留时间的显著增加相关。
