放射科医生的肿瘤血管生成成像——第2部分：临床应用
Imaging of Tumor Angiogenesis for Radiologists--Part 2: Clinical Utility.
作者信息
García-Figueiras Roberto, Padhani Anwar R, Beer Ambros J, Baleato-González Sandra, Vilanova Joan C, Luna Antonio, Oleaga Laura, Gómez-Caamaño Antonio, Koh Dow-Mu
机构信息
Department of Radiology, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
Paul Strickland Scanner Centre, Mount Vernon Cancer Centre, Northwood, Middlesex, England, UK.
出版信息
Curr Probl Diagn Radiol. 2015 Sep-Oct;44(5):425-36. doi: 10.1067/j.cpradiol.2015.02.009. Epub 2015 Mar 6.
Angiogenesis is a key cancer hallmark involved in tumor growth and metastasis development. Angiogenesis and tumor microenvironment significantly influence the response of tumors to therapies. Imaging techniques have changed our understanding of the process of angiogenesis, the resulting vascular performance, and the tumor microenvironment. This article reviews the status and potential clinical value of the imaging modalities used to assess the status of tumor vasculature in vivo, before, during, and after treatment.
血管生成是肿瘤生长和转移过程中的一个关键癌症特征。血管生成和肿瘤微环境显著影响肿瘤对治疗的反应。成像技术改变了我们对血管生成过程、由此产生的血管性能以及肿瘤微环境的理解。本文综述了用于评估体内肿瘤血管系统在治疗前、治疗期间和治疗后状态的成像模态的现状及其潜在临床价值。
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