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[针对位于胃中部的进展期癌症的合理外科手术]

[Rational surgical operations for advanced cancers located in the middle of the stomach].

作者信息

Furukawa H, Iwanaga T, Hiratsuka M, Imaoka S, Fukuda I, Kabuto T, Koyama H

机构信息

Department of Surgery, Center for Adult Diseases, Osaka, Japan.

出版信息

Nihon Geka Gakkai Zasshi. 1989 Sep;90(9):1322-5.

PMID:2586412
Abstract

Before 1982, total gastrectomy with pancreaticosplenectomy was performed for advanced gastric carcinoma which exposed to the serosa and was located in the middle of the stomach (M). The results of that surgical treatment were evaluated, and new surgical approaches were expected to provide a much better prognosis to patients. (1) A radical surgical operation, left upper abdominal evisceration + Appleby's method (LUAE + Apl), was tried for Borrmann type 4 gastric cancers from 1983. The 3-year survival after LUAE + Apl (77.9%) was better than that after total gastrectomy with pancreaticosplenectomy (35.0%) (p less than 0.05). In terms of the postoperative condition, no significant differences were observed between both operations. (2) As a conservative operation, total gastrectomy with resection of the spleen and splenic artery (Group A) was compared with total gastrectomy plus pancreaticosplenectomy (Group B) in patients with advanced gastric carcinoma other than Borrmann type 4. The 5-year survival was similar in both groups. The incidence of postoperative disorders was lower in Group A than in Group B (p less than 0.05). LUAE + Apl for Borrmann type 4 and total gastrectomy with resection of the spleen and splenic artery for the other advanced gastric cancers led to good results. These rational surgical operations will be necessary to achieve a good quality of life for the patients.

摘要

1982年以前,对于侵犯至浆膜层且位于胃中部(M)的进展期胃癌,施行全胃切除术加胰脾切除术。对该手术治疗结果进行了评估,并期望新的手术方法能为患者带来更好的预后。(1)1983年起,对于Borrmann 4型胃癌尝试了一种根治性手术,即左上腹脏器切除术+阿普尔比氏法(LUAE+Apl)。LUAE+Apl术后3年生存率(77.9%)高于全胃切除术加胰脾切除术(35.0%)(p<0.05)。在术后状况方面,两种手术之间未观察到显著差异。(2)作为一种保守手术,对除Borrmann 4型以外的进展期胃癌患者,比较了全胃切除术加脾和脾动脉切除术(A组)与全胃切除术加胰脾切除术(B组)。两组5年生存率相似。A组术后并发症发生率低于B组(p<0.05)。Borrmann 4型采用LUAE+Apl,其他进展期胃癌采用全胃切除术加脾和脾动脉切除术均取得了良好效果。这些合理的手术对于提高患者生活质量是必要的。

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