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[胃癌保守手术与扩大手术的临床病理研究]

[A clinicopathological study on conservative surgery and extended surgery for gastric cancer].

作者信息

Furukawa H, Iwanaga T, Hiratsuka M, Imaoka S, Fukuda I, Ishikawa O, Kabuto T

机构信息

Department of Surgery, The Center for Adult Diseases, Osaka, Japan.

出版信息

Nihon Geka Gakkai Zasshi. 1988 Sep;89(9):1531-4.

PMID:3226420
Abstract

There are two problems in conservative surgery for early gastric cancer. 1) To resect the stomach at a sufficient surgical margin, brushing cytodiagnosis of the gastric mucosa and frozen section examination at the stump are performed during operation. After all these examinations, the stomach is resected at a sufficient margin because of the possibility of multifocal cancer. 2) Regarding lymph node dissection, only N1 lymph nodes are to be removed in minute cancer (less than 5mm in diameter) which have no lymph node metastasis (0%). Thirty-one cases of Borrmann type 4 gastric cancer which underwent left upper abdominal evisceration plus Appleby's method (LUAE + Apl) were compared with 31 patients who had undergone total gastrectomy with pancreatico-splenectomy (TG) before LUAE + Apl series. The 3-year survival rate in stage II-III cases was higher with LUAE + Apl (77.8%) than with TG (35.0%). There was no difference between the two groups in the incidence of postoperative complications or the function after operation. Angiography must be performed before conducting operations by LUAE + Apl preventing liver necrosis. And for patients aged over 70, we propose to reduce the procedure of LUAE + Apl.

摘要

早期胃癌的保守手术存在两个问题。1)为了在足够的手术切缘切除胃,术中要对胃黏膜进行刷片细胞诊断,并对残端进行冰冻切片检查。经过所有这些检查后,由于存在多灶性癌的可能性,要在足够的切缘切除胃。2)关于淋巴结清扫,对于直径小于5mm且无淋巴结转移(0%)的微小癌,仅切除N1淋巴结。将31例接受左上腹脏器切除术加阿普尔比氏法(LUAE + Apl)的Borrmann 4型胃癌患者与LUAE + Apl系列手术前接受全胃切除术加胰脾切除术(TG)的31例患者进行比较。II - III期病例中,LUAE + Apl组的3年生存率(77.8%)高于TG组(35.0%)。两组术后并发症发生率和术后功能无差异。在进行LUAE + Apl手术前必须进行血管造影,以防止肝坏死。对于70岁以上的患者,我们建议简化LUAE + Apl手术步骤。

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