巩膜镜对圆锥角膜患者角膜曲率和角膜厚度的影响。
Scleral lens influence on corneal curvature and pachymetry in keratoconus patients.
作者信息
Soeters Nienke, Visser Esther Simone, Imhof Saskia M, Tahzib Nayyirih G
机构信息
Department of Ophthalmology, University Medical Center Utrecht, Utrecht, The Netherlands.
Department of Ophthalmology, University Medical Center Utrecht, Utrecht, The Netherlands; Visser Contact Lens Practice, Nijmegen, The Netherlands.
出版信息
Cont Lens Anterior Eye. 2015 Aug;38(4):294-7. doi: 10.1016/j.clae.2015.03.006. Epub 2015 Apr 10.
OBJECTIVES
To investigate the influence of full scleral lenses on corneal curvature and pachymetry in keratoconus patients.
METHODS
In this intervention study, 20 eyes of 14 patients were measured by Scheimpflug imaging (Pentacam HR, Oculus) at two time points: directly and ≥1 week after scleral lens removal. Steep, flat and maximal keratometry (K(steep), K(flat) and K(max)) and optical pachymetry were analyzed. A generalized estimating equation analysis was performed to correct for paired eyes.
RESULTS
Directly after scleral lens removal, all three curvature parameters were significantly flatter compared to ≥1 week after scleral lens removal. Average K(steep) was 0.7 diopter (D) lower (P<0.001), average K(flat) was 0.5D lower (P=0.037) and average K(max) was 1.1D lower (P<0.001). Directly after scleral lens removal, average optical pachymetry was ±2.5% higher (P<0.001) compared to ≥1 week after scleral lens removal.
CONCLUSIONS
Although scleral lenses do not mechanically touch the cornea, curvature and pachymetry seem to be influenced by scleral lens wear in keratoconus patients. The duration of these changes remain unclear.
目的
研究全巩膜镜片对圆锥角膜患者角膜曲率和角膜厚度测量的影响。
方法
在这项干预性研究中，对14例患者的20只眼睛在两个时间点采用眼前节分析系统（Pentacam HR，Oculus公司）进行测量：巩膜镜片摘除后即刻以及摘除后≥1周。分析陡峭、平坦和最大角膜曲率（K(steep)、K(flat)和K(max)）以及光学角膜厚度测量值。采用广义估计方程分析对双眼进行校正。
结果
巩膜镜片摘除后即刻，与摘除后≥1周相比，所有三个曲率参数均显著变平。平均K(steep)降低0.7屈光度（D）（P<0.001），平均K(flat)降低0.5D（P=0.037），平均K(max)降低1.1D（P<0.001）。巩膜镜片摘除后即刻，平均光学角膜厚度测量值比摘除后≥1周时高出±2.5%（P<0.001）。
结论
尽管巩膜镜片并未机械接触角膜，但圆锥角膜患者佩戴巩膜镜片似乎会影响角膜曲率和角膜厚度测量值。这些变化的持续时间尚不清楚。
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