Fragua V, Barroeta A C, Manzanilla E G, Codony R, Villaverde C
Departament de Ciència Animal i dels Aliments, Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain.
J Anim Physiol Anim Nutr (Berl). 2015 Apr;99 Suppl S1:48-59. doi: 10.1111/jpn.12312.
Esterified fatty acid oils (EAOs) are obtained from esterification of vegetable acid oils with glycerol. These fat sources have the same fatty acid (FA) composition as their respective native oils but new chemical properties. Several studies have confirmed the potential of medium-chain fatty acids (MCFA) to reduce fat mass (FM) in humans and rodents. This study investigates the use of EAOs with different MCFA proportions on food preferences, digestibility and weight loss management in dogs. A basal diet was supplemented with 8% of three different fat sources: C0: soya bean-canola EAO, C20: soya bean-canola (80%) coconut (20%) EAO and C40: soya bean-canola (60%) coconut (40%) EAO. Food preference of these EAOs was tested using a two-pan preference test. Dogs presented a higher daily food intake of C20 and C40 compared to C0 (C20: 155 ± 18.6 g vs. C0: 17 ± 7.0 g, p < 0.001; C40: 117 ± 13.9 g vs. C0: 28 ± 10.5 g, p < 0.05 respectively). Also, the digestibility of the three experimental diets was tested. C20 and C40 showed higher ether extract, total FA and saturated FA digestibilities (p < 0.05) than C0 diet. Lastly, the three diets were investigated in a 14-week weight loss study, following 16 weeks of ad libitum feeding to induce overweight condition. Body weight (BW) reduction was lower (C0: 20.1 ± 2.32%, C20: 14.6 ± 1.43% and C40: 15.7 ± 1.23%, p < 0.05) and FM was higher (FM, 18.7 ± 3.42%, 27.9 ± 3.90% and 28.2 ± 2.88% for C0, C20 and C40, respectively, p < 0.05) for diets C20 and C40 than for C0. Feeding diets with MCFA at these inclusion levels to experimentally overweight dogs during 14 weeks do not result in faster weight loss compared to unsaturated long-chain FA.
酯化脂肪酸油（EAOs）是通过植物油酸与甘油的酯化反应获得的。这些脂肪来源与其各自的天然油具有相同的脂肪酸（FA）组成，但具有新的化学性质。多项研究证实了中链脂肪酸（MCFA）在减少人类和啮齿动物脂肪量（FM）方面的潜力。本研究调查了不同MCFA比例的EAOs对犬类食物偏好、消化率和体重减轻管理的影响。基础日粮中添加了8%的三种不同脂肪来源：C0：大豆-油菜籽EAO、C20：大豆-油菜籽（80%）椰子（20%）EAO和C40：大豆-油菜籽（60%）椰子（40%）EAO。使用双盘偏好试验测试了这些EAOs的食物偏好。与C0相比，犬类对C20和C40的每日食物摄入量更高（C20：155±18.6克对C0：17±7.0克，p<0.001；C40：117±13.9克对C0：28±10.5克，p<0.05）。此外，还测试了三种实验日粮的消化率。C20和C40的乙醚提取物、总FA和饱和FA消化率（p<0.05）高于C0日粮。最后，在一项为期14周的体重减轻研究中对三种日粮进行了研究，此前进行了16周的自由采食以诱导超重状态。与不饱和长链FA相比，在14周内给实验性超重犬喂食这些添加水平的MCFA日粮不会导致更快的体重减轻。（C0：体重减轻20.1±2.32%，C20：14.6±1.43%，C40：15.7±1.23%，p<0.05；C0、C20和C40的FM分别为18.7±3.42%、27.9±3.90%和28.2±2.88%，p<0.05） 。
