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儿童期心理创伤暴露与自杀未遂风险:精神障碍的调节作用。

Childhood exposure to psychological trauma and the risk of suicide attempts: the modulating effect of psychiatric disorders.

机构信息

Department of Psychiatry, Seoul National Hospital, Seoul, Republic of Korea.

Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

出版信息

Psychiatry Investig. 2015 Apr;12(2):171-6. doi: 10.4306/pi.2015.12.2.171. Epub 2014 Dec 12.

Abstract

OBJECTIVE

We examined whether childhood exposure to psychological trauma is associated with greater suicidality and whether specific psychiatric disorders modulate this association in a representative sample of Korean adults.

METHODS

The Korean version of the Composite International Diagnostic Interview 2.1 was administered to 6,027 subjects aged 18-74 years. Subjects who experienced a traumatic event before the age of 18 years, the childhood-trauma-exposure group, were compared with controls without childhood trauma exposure.

RESULTS

Childhood exposure to psychological trauma was associated with lifetime suicidal ideation (OR=3.19, 95% CI=2.42-4.20), suicide plans (OR=4.15, 95% CI=2.68-6.43), and suicide attempts (OR=4.52, 95% CI=2.97-6.88). These associations weakened after further adjustment for any psychiatric disorders, but they were not eliminated. The risk of suicide attempts related to childhood trauma increased with the presence of a concurrent alcohol use, depressive, or eating disorder.

CONCLUSION

In terms of clinical implications, patients with these disorders who have a history of childhood trauma should be carefully assessed for their suicide risk and aggressively treated for psychiatric disorders.

摘要

目的

我们研究了童年期心理创伤暴露与更高自杀意念之间的关系,以及特定精神障碍是否会调节这种关联,研究对象为韩国代表性成年人样本。

方法

6027 名 18-74 岁的研究对象完成了韩国版复合国际诊断访谈 2.1。将经历过 18 岁前创伤事件的受试者(儿童期创伤暴露组)与无儿童期创伤暴露的对照组进行比较。

结果

童年期心理创伤暴露与终生自杀意念(OR=3.19,95%CI=2.42-4.20)、自杀计划(OR=4.15,95%CI=2.68-6.43)和自杀未遂(OR=4.52,95%CI=2.97-6.88)相关。进一步调整任何精神障碍后,这些关联减弱,但并未消除。与儿童期创伤相关的自杀未遂风险随着同时存在酒精使用障碍、抑郁障碍或进食障碍而增加。

结论

就临床意义而言,有这些障碍且有儿童期创伤史的患者应仔细评估其自杀风险,并积极治疗精神障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a591/4390586/904db8c144db/pi-12-171-g001.jpg

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