一名患有抗PL-7合成酶综合征的患者产后发生过敏性紫癜性肾炎。
Henoch-Schönlein purpura nephritis occurring postpartum in a patient with anti-PL-7 anti-synthetase syndrome.
作者信息
Nagai Kojiro, Kishi Jun, Morizumi Shun, Minakuchi Jun, Bando Yoshimi, Nishioka Yasuhiko, Doi Toshio
机构信息
a Department of Nephrology , Tokushima University Hospital , Tokushima , Japan.
b Department of Respiratory Medicine and Rheumatology , Tokushima University Hospital , Tokushima , Japan.
出版信息
Mod Rheumatol. 2017 Sep;27(5):910-913. doi: 10.3109/14397595.2015.1038879. Epub 2015 May 28.
A 37-year-old pregnant woman developed purpura which was subsequently diagnosed as Henoch-Schönlein purpura (HSP). After childbirth, the patient developed proteinuria and hematuria. Further examination revealed that the HSP nephritis (HSPN) was associated with anti-threonyl-tRNA synthetase anti-synthetase syndrome. The onset of HSPN during pregnancy or after childbirth is rare. Moreover, to our knowledge, this is the first case to describe renal involvement in anti-synthetase syndrome.
一名37岁的孕妇出现紫癜，随后被诊断为过敏性紫癜（HSP）。产后，该患者出现蛋白尿和血尿。进一步检查发现，HSP肾炎（HSPN）与抗苏氨酰-tRNA合成酶抗合成酶综合征相关。HSPN在孕期或产后发病较为罕见。此外，据我们所知，这是首例描述抗合成酶综合征肾脏受累情况的病例。
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