Werncke Thomas, von Falck Christian, Luepke Matthias, Stamm Georg, Wacker Frank K, Meyer Bernhard Christian
From the *Institute of Diagnostic and Interventional Radiology, Hannover Medical School; and †University of Veterinary Medicine, Hannover Institute for General Radiology and Medical Physics, Hannover, Germany.
Invest Radiol. 2015 Aug;50(8):514-21. doi: 10.1097/RLI.0000000000000158.
The aim of this study was to assess the potential for radiation dose reduction in collimated C-arm computed tomography (CACT) while maintaining the image quality of the full field of view (FFOV) acquisition.
A whole-body anthropomorphic phantom representing a 70-kg male was used in this study. The upper abdomen of the phantom was imaged using an angiographic system (Artis Zeego Q; Siemens Healthcare, Germany) with either the standard detector radiation dose level (RDL; D100, 360 nGy) or 14 experimental reduced RDLs ranging from 95% (D95, 342 nGy) to 30% D100 (D30, 108 nGy). Either the FFOV (craniocaudal coverage, 18 cm) or a collimated field of view (CFOV; craniocaudal coverage, 6 cm) was applied. The organ dose was measured using thermoluminescence detector dosimetry, and the mean effective dose was computed according to the recommendations by the International Commission on Radiological Protection Publication 103. To compare the CFOV and the FFOV data sets, image quality was assessed in terms of high- and low-contrast resolution by calculating the modulation transfer function using the wire method as well as the image noise, signal-to-noise ratio, and contrast-to-noise ratio using a low-contrast insert placed in the upper abdomen (Δ50 HU).
Collimated imaging (CFOV) covering 33% of the FFOV led to an increase in the x-ray tube output of 152% for CFOV (D100; FFOV, 95.5 mGy; CFOV, 147.7 mGy) to maintain the detector dose. The mean effective dose of D100 was 6.0 mSv (male) and 6.2 mSv (female) for the FFOV and 3.7 mSv (male) and 4.1 mSv (female) for the CFOV. High-contrast resolution was comparable for all acquisition protocols (mean 10% modulation transfer function ± 95% confidence interval; FFOV, 8.8 ± 0.1 line pairs/cm; CFOV, 8.8 ± 0.1 line pairs/cm). Low-contrast resolution was superior for the CFOV compared with that for the FFOV for each RDL (D100; image noise: FFOV, 34 ± 2 HU; CFOV, 22 ± 1 HU; contrast-to-noise ratio: FFOV, 1.3 ± 0.2; CFOV, 1.8 ± 0.3). Low-contrast resolution of the standard (D100) FFOV acquisition was achieved for the CFOV at 84% D100 of the FFOV and 54% D100 of the CFOV. Therefore, collimation up to 33% of the FFOV combined with the lower detector dose allows overall reduction of a patient's radiation exposure to 33% × 84% = 28% compared with FFOV acquisition. In the upper abdomen, this results in a nearly 50% reduction of the mean effective radiation dose (male, 2.0 mSv; female, 2.2 mSv) without loss of image quality compared with the standard FFOV acquisition.
Craniocaudal collimation in CACT should be used whenever possible to increase the image quality and reduce the patient's overall radiation exposure. Therefore, new smart acquisition protocols are required for collimated CACT to improve the trade-off between radiation exposure and image quality requirements considering the collimation used.
本研究旨在评估在保持全视野(FFOV)采集图像质量的同时,准直型C形臂计算机断层扫描(CACT)降低辐射剂量的潜力。
本研究使用了一个代表70千克男性的全身仿真人体模型。使用血管造影系统(Artis Zeego Q;德国西门子医疗)对模型的上腹部进行成像,采用标准探测器辐射剂量水平(RDL;D100,360 nGy)或14种实验性降低的RDL,范围从95%(D95,342 nGy)到30% D100(D30,108 nGy)。应用FFOV(头足覆盖范围,18厘米)或准直视野(CFOV;头足覆盖范围,6厘米)。使用热释光探测器剂量测定法测量器官剂量,并根据国际放射防护委员会第103号出版物的建议计算平均有效剂量。为了比较CFOV和FFOV数据集,通过使用线方法计算调制传递函数以及使用放置在上腹部的低对比度插入物(Δ50 HU)计算图像噪声、信噪比和对比度噪声比,从高对比度分辨率和低对比度分辨率方面评估图像质量。
覆盖FFOV 33%的准直成像(CFOV)导致CFOV的X射线管输出增加152%(D100;FFOV,95.5 mGy;CFOV,147.7 mGy)以维持探测器剂量。FFOV的D100平均有效剂量男性为6.0 mSv,女性为6.2 mSv,CFOV的平均有效剂量男性为3.7 mSv,女性为4.1 mSv。所有采集方案的高对比度分辨率相当(平均10%调制传递函数±95%置信区间;FFOV,8.8±0.1线对/厘米;CFOV,8.8±0.1线对/厘米)。与FFOV相比,每个RDL下CFOV的低对比度分辨率更高(D100;图像噪声:FFOV,34±2 HU;CFOV,22±1 HU;对比度噪声比:FFOV,1.3±0.2;CFOV,1.8±0.3)。CFOV在FFOV的84% D100和CFOV的54% D100时实现了标准(D100)FFOV采集的低对比度分辨率。因此,与FFOV采集相比,高达FFOV 33%的准直与较低的探测器剂量相结合可使患者的辐射暴露总体降低至33%×84% = 28%。在上腹部,与标准FFOV采集相比,这导致平均有效辐射剂量降低近50%(男性,2.0 mSv;女性,2.2 mSv)且不损失图像质量。
只要有可能,CACT中应使用头足准直以提高图像质量并降低患者的总体辐射暴露。因此,需要新的智能采集方案用于准直型CACT,以在考虑所使用的准直情况下改善辐射暴露与图像质量要求之间的权衡。