利用红外（IR）显微光谱技术进行抗癌药物的临床前筛选。

Preclinical screening of anticancer drugs using infrared (IR) microspectroscopy.

机构信息

University of Manchester, Brunswick Street, Manchester M13 9PL, UK; WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, UK.

WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, UK; Centre for Materials Science, Division of Chemistry, School of Forensic and Investigative Sciences, University of Central Lancashire (UCLan), Preston PR1 2HE, UK.

出版信息

Trends Biotechnol. 2015 Aug;33(8):429-30. doi: 10.1016/j.tibtech.2015.03.010. Epub 2015 Apr 10.

DOI:10.1016/j.tibtech.2015.03.010

PMID:25869233

Abstract

High-throughput label-free technologies such as IR microscopy can objectively assess the effect of drugs upon cellular systems, offering the potential of a valuable preclinical tool that can aid in the drug development process.

摘要

高通量无标记技术，如红外显微镜，可以客观地评估药物对细胞系统的影响，为药物开发过程提供有价值的临床前工具的潜力。