Konert Tom, Vogel Wouter, MacManus Michael P, Nestle Ursula, Belderbos José, Grégoire Vincent, Thorwarth Daniela, Fidarova Elena, Paez Diana, Chiti Arturo, Hanna Gerard G
Department of Nuclear Medicine, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Department of Nuclear Medicine, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Radiother Oncol. 2015 Jul;116(1):27-34. doi: 10.1016/j.radonc.2015.03.014. Epub 2015 Apr 10.
This document describes best practice and evidence based recommendations for the use of FDG-PET/CT for the purposes of radiotherapy target volume delineation (TVD) for curative intent treatment of non-small cell lung cancer (NSCLC). These recommendations have been written by an expert advisory group, convened by the International Atomic Energy Agency (IAEA) to facilitate a Coordinated Research Project (CRP) aiming to improve the applications of PET based radiation treatment planning (RTP) in low and middle income countries. These guidelines can be applied in routine clinical practice of radiotherapy TVD, for NSCLC patients treated with concurrent chemoradiation or radiotherapy alone, where FDG is used, and where a calibrated PET camera system equipped for RTP patient positioning is available. Recommendations are provided for PET and CT image visualization and interpretation, and for tumor delineation using planning CT with and without breathing motion compensation.
本文件描述了使用氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（FDG-PET/CT）为非小细胞肺癌（NSCLC）根治性治疗进行放射治疗靶区勾画（TVD）的最佳实践和循证建议。这些建议由国际原子能机构（IAEA）召集的一个专家咨询小组撰写，以推动一项旨在改善中低收入国家基于PET的放射治疗计划（RTP）应用的协调研究项目（CRP）。这些指南可应用于NSCLC患者接受同步放化疗或单纯放疗的放射治疗TVD常规临床实践中，其中使用了FDG，且有配备用于RTP患者定位的校准PET相机系统。针对PET和CT图像的可视化与解读，以及使用有和没有呼吸运动补偿的计划CT进行肿瘤勾画提供了建议。
