Canavese G, Catturich A, Battistini G, Caroti C, Pronzato P, Gardin G, Amoroso D, Bertelli G, Conte P F, Tomao S
Divisioni di Oncologia Chirurgica e, Instituto Nazionale par la Ricerca sul Cancro, Genova, Italia.
Oncology. 1989;46(6):353-6. doi: 10.1159/000226749.
Sixty patients with stage IIIA and IIIB breast cancer have been treated with a combined modality approach including induction chemotherapy, surgery and adjuvant chemotherapy: 74.5% of patients achieved an objective response after 3 cycles of induction chemotherapy, and 98.3% of patients were rendered disease-free after induction chemotherapy and surgery or radiotherapy; at 4 years, actuarial survival and disease-free survival are 71.5% and 43%, respectively. These results are significantly better than our historical control, and locally advanced breast cancer must now be considered a curable disease when treated with an aggressive multimodal approach.
