Cochrane系统评价在妇科癌症中的结论性：一项系统分析。
Conclusiveness of the Cochrane reviews in gynaecological cancer: A systematic analysis.
作者信息
Yin Shande, Chuai Yunhai, Wang Aiming, Zhang Lanmei
机构信息
Department of Obstetrics and Gynaecology, Navy General Hospital, Beijing, China.
Department of Obstetrics and Gynaecology, Navy General Hospital, Beijing, China
出版信息
J Int Med Res. 2015 Jun;43(3):311-5. doi: 10.1177/0300060515574922. Epub 2015 Apr 13.
OBJECTIVE
To assess the conclusiveness of Cochrane reviews in the field of gynaecological cancer.
METHODS
The Cochrane Library was searched for reviews regarding gynaecological cancer published between 1 January 2000 and 1 November 2014. Data were extracted from each paper and the conclusiveness of each review was assessed.
RESULTS
The study included 66 reviews, 41 (62.1%) of which were conclusive. Of these, 58 included randomized controlled trials (RCTs), 37 (63.8%) of which were conclusive. Conclusive reviews of RCTs included significantly more patients than inconclusive reviews, but there was no difference in the number of included studies. Of the eight reviews of nonrandomized studies, four (50.0%) were conclusive. The majority of reviews recognized the need for additional studies.
CONCLUSIONS
In the field of gynaecological cancer, reviews are more likely to be conclusive when they include RCTs, as well as large numbers of patients.
目的
评估Cochrane系统评价在妇科癌症领域的结论性。
方法
检索Cochrane图书馆，查找2000年1月1日至2014年11月1日期间发表的关于妇科癌症的系统评价。从每篇论文中提取数据，并评估每个系统评价的结论性。
结果
该研究纳入了66篇系统评价，其中41篇（62.1%）具有结论性。其中，58篇纳入了随机对照试验（RCT），37篇（63.8%）具有结论性。RCT的结论性系统评价纳入的患者明显多于非结论性系统评价，但纳入研究的数量没有差异。在八项非随机研究的系统评价中，四项（50.0%）具有结论性。大多数系统评价认识到需要更多的研究。
结论
在妇科癌症领域，当系统评价纳入RCT以及大量患者时，更有可能具有结论性。
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