Chanana Nitin, Day Ronald W, McGough Edwin C, Burch Phillip T
Department of Pediatrics, Division of Cardiology, Primary Children's Hospital, University of Utah, Salt Lake City, UT, USA
Department of Pediatrics, Division of Cardiology, Primary Children's Hospital, University of Utah, Salt Lake City, UT, USA.
World J Pediatr Congenit Heart Surg. 2015 Apr;6(2):220-5. doi: 10.1177/2150135115574532.
Axillary or brachial arteriovenous fistulae are occasionally created to improve systemic oxygen saturation in patients with functionally univentricular circulation after superior cavopulmonary anastomosis. Different techniques of fistula construction may account for the conflicting results. We sought to determine the impact of axillary arteriovenous fistula on systemic oxygen saturation and survival before subsequent palliation or heart transplantation.
Medical records of patients who underwent a side-to-side anastomosis between an adjacent axillary artery and vein for cyanosis after superior cavopulmonary anastomosis between 1991 and 2010 were reviewed.
The median age (n = 23) at the time of fistula creation was 54 months (4-278 months). There was no operative mortality. The median duration of fistula patency was 48 months (1-174 months). Oxygen saturation improved from 71% ± 10% preoperatively to 84% ± 4% early (P < .05) and 81% ± 4% long term after the arteriovenous fistula (P < .05). Twelve patients underwent additional surgery (total cavopulmonary anastomosis 6, partial biventricular repair 2, and heart transplantation 4) after an interval of 10 to 141 months. Six patients are alive with a patent fistula without subsequent interventions after an interval of 48 to 174 months. Two patients with spontaneous closure or device closure of the fistula are alive after an interval of 76 to 80 months without subsequent interventions. Three deaths occurred with a patent fistula without subsequent interventions after an interval of 1 to 84 months.
Systemic oxygen saturation improved with creation of an axillary arteriovenous fistula after superior cavopulmonary anastomosis. The fistula extended the duration of this stage of palliation without precluding the option for additional palliation or heart transplantation.
在实施上腔静脉-肺动脉吻合术后,对于功能单心室循环的患者,偶尔会建立腋动静脉或肱动静脉瘘以提高全身氧饱和度。不同的瘘管构建技术可能导致结果相互矛盾。我们试图确定腋动静脉瘘对全身氧饱和度以及后续姑息治疗或心脏移植前生存率的影响。
回顾了1991年至2010年间因上腔静脉-肺动脉吻合术后发绀而接受相邻腋动脉和静脉端侧吻合的患者的病历。
建立瘘管时的中位年龄(n = 23)为54个月(4 - 278个月)。无手术死亡。瘘管通畅的中位持续时间为48个月(1 - 174个月)。氧饱和度从术前的71%±10%早期改善至84%±4%(P <.05),动静脉瘘建立后长期为81%±4%(P <.05)。12例患者在间隔10至141个月后接受了额外手术(全腔静脉-肺动脉吻合术6例、部分双心室修复2例、心脏移植4例)。6例患者在间隔48至174个月后,瘘管通畅且未进行后续干预,仍存活。2例瘘管自发闭合或通过装置闭合的患者在间隔76至80个月后存活,未进行后续干预。3例患者在间隔1至84个月后,瘘管通畅但未进行后续干预,死亡。
上腔静脉-肺动脉吻合术后建立腋动静脉瘘可改善全身氧饱和度。该瘘管延长了这一姑息治疗阶段的持续时间,且不排除进行额外姑息治疗或心脏移植的选择。