Jazaeri Mina, Malekzadeh Hosein, Abdolsamadi Hamidreza, Rezaei-Soufi Loghman, Samami Mohammad
Department of Oral Medicine, School of Dentistry, Hamadan University of Medical Sciences, Hamadan, Iran.
Department of Oral Medicine, School of Dentistry, Jundi Shapour University of Medical Sciences, Ahvaz, Iran.
Cell J. 2015 Spring;17(1):159-62. doi: 10.22074/cellj.2015.523. Epub 2015 Apr 8.
Although salivary alkaline phosphatase (ALP) can balance deand remineralization processes of enamel, there is no evidence regarding its effects on the concentrations of calcium and phosphate in saliva. The present study aims to determine the relationship between salivary ALP activity and the concentrations of calcium and phosphate in saliva. In this cross-sectional study, we evaluated salivary markers in 120 males, ages 19 to 44 years. All participants provided 5 mL of unstimulated whole saliva and the level of enzyme activity as well as calcium and phosphate concentrations were measured using a colorimetric method. Data were gathered and analyzed by statistical package for social sciences (SPSS) 13.00 using Pearson correlation test. A p value of <0.05 was considered statistically significant. The mean age of participants in the present study was 32.95 ± 8.09 years. The mean pH of saliva was 6.65 ± 0.62. Salivary parameters included average ALP activity (5.04 ± 1.866 U/dL), calcium (4.77 ± 0.877 mg/dL) and phosphate (10.38 ± 2.301 mg/dL). Pearson correlation test showed no significant relationship between ALP activity and calcium and phosphate concentrations in saliva (p>0.05). According to the results of the present study, there was no significant relation between salivary ALP activity and calcium and phosphate concentrations in saliva. However, further research is highly recommended.
尽管唾液碱性磷酸酶（ALP）可以平衡牙釉质的脱矿质和再矿化过程，但尚无证据表明其对唾液中钙和磷浓度的影响。本研究旨在确定唾液ALP活性与唾液中钙和磷浓度之间的关系。在这项横断面研究中，我们评估了120名年龄在19至44岁之间男性的唾液标志物。所有参与者均提供了5 mL非刺激性全唾液，并使用比色法测量了酶活性水平以及钙和磷的浓度。使用社会科学统计软件包（SPSS）13.00收集数据并进行Pearson相关性检验分析。p值<0.05被认为具有统计学意义。本研究中参与者的平均年龄为32.95±8.09岁。唾液的平均pH值为6.65±0.62。唾液参数包括平均ALP活性（5.04±1.866 U/dL）、钙（4.77±0.877 mg/dL）和磷（10.38±2.301 mg/dL）。Pearson相关性检验显示，ALP活性与唾液中钙和磷浓度之间无显著关系（p>0.05）。根据本研究结果，唾液ALP活性与唾液中钙和磷浓度之间无显著关系。然而，强烈建议进行进一步研究。
