Poros Eszter, Kurin-Csörgei Krisztina
Acta Pharm Hung. 2014;84(4):144-52.
The mechanisms of the complicated periodical phenomenas in the nature (e.g. hearth beat, sleep cycle, circadian rhythms, etc) could be understood with using the laws of nonlinear chemical systems. In this article the newest result in the research of the subfield of nonlinear chemical dynamics aimed at constructing oscillatory chemical reactions, which are novel either in composition or in configuration, are presented. In the introductory part the concept of chemical periodicity is defined, then the forms as it can appear in time and space and the methods of their study are discussed. Detailed description of the experimental work that has resulted in two significant discoveries is provided. A method was developed to design pH-oscillators which are capable of operating under close conditions. The batch pH-oscillators are more convenient to use in some proposed applications than the equivalent CSTR variant. A redox oscillator that is new in composition was found. The permanganate oxidation of some amino acids was shown to take place according to oscillatory kinetics in a narrow range of the experimental parameters. The KMnO4 - glycine - Na2HPO4 system represents the first example in the family of manganese based oscillators where amino acids is involved. In the conclusion formal analogies between the simple chemical and some more complicated biological oscillatory phenomena are mentioned and the possibility of modeling periodic processes with the use of information gained from the studies of chemical oscillations is pointed out.
自然界中复杂周期性现象（如心跳、睡眠周期、昼夜节律等）的机制可以通过运用非线性化学系统的规律来理解。本文展示了非线性化学动力学子领域研究的最新成果，该研究旨在构建在组成或结构上新颖的振荡化学反应。在引言部分，定义了化学周期性的概念，接着讨论了其在时间和空间中可能出现的形式以及研究方法。提供了导致两项重大发现的实验工作的详细描述。开发了一种设计能够在封闭条件下运行的pH振荡器的方法。在一些建议的应用中，间歇式pH振荡器比等效的连续搅拌釜式反应器（CSTR）变体更便于使用。发现了一种组成新颖的氧化还原振荡器。在狭窄的实验参数范围内，某些氨基酸的高锰酸钾氧化反应表现出振荡动力学。KMnO₄ - 甘氨酸 - Na₂HPO₄系统是涉及氨基酸的锰基振荡器家族中的第一个例子。在结论部分，提到了简单化学振荡与一些更复杂生物振荡现象之间的形式类比，并指出了利用从化学振荡研究中获得的信息对周期性过程进行建模的可能性。
