Torossian Nouritza M, Wallace Roy T, Hwu Wen-Jen, Bedikian Agop Y
Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France.
Retina Consultants of Nashville, Nashville, TN, USA.
Case Rep Oncol Med. 2015;2015:427163. doi: 10.1155/2015/427163. Epub 2015 Mar 22.
Many types of cancers metastasize to the eye. However, uveal melanoma metastasizing to the contralateral choroid is very rare. We report the case of a 68-year-old man with history of treated uveal melanoma of the right eye that developed metastasis to the liver and the choroid of the left eye. Ten years earlier, he was diagnosed to have uveal melanoma of the right eye and was initially treated with plaque radiotherapy. Two years later, upon progression of the disease in the right eye he had enucleation of the eye. We describe the patient's clinical history, the diagnosis of recurrent disease in the contralateral eye, therapy of the left eye, and systemic metastasis. In addition, we reviewed the published medical literature and described the recent advances in the management of uveal melanoma.
许多类型的癌症会转移至眼部。然而,葡萄膜黑色素瘤转移至对侧脉络膜极为罕见。我们报告一例68岁男性病例,其右眼曾患葡萄膜黑色素瘤并接受治疗,之后发生了肝转移及左眼脉络膜转移。十年前,他被诊断为右眼葡萄膜黑色素瘤,最初接受了敷贴放疗。两年后,右眼病情进展,他接受了眼球摘除术。我们描述了该患者的临床病史、对侧眼复发性疾病的诊断、左眼的治疗以及全身转移情况。此外,我们查阅了已发表的医学文献,并阐述了葡萄膜黑色素瘤治疗方面的最新进展。