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心包后切开术联合心包内置管对冠状动脉手术后心包积液、心房颤动及急性肾损伤发生的预防作用:一项前瞻性、随机、对照试验

The Preventive Effects of Posterior Pericardiotomy with Intrapericardial Tube on the Development of Pericardial Effusion, Atrial Fibrillation, and Acute Kidney Injury after Coronary Artery Surgery: A Prospective, Randomized, Controlled Trial.

作者信息

Kaya Mehmet, Utkusavaş Ayfer, Erkanlı Korhan, Güler Salih, Kyaruzi Mugisha, Birant Ali, Karaçalılar Mehmet, Akkuş Murat, Bakır İhsan

机构信息

Department of Cardiovascular Surgery, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.

Department of Pulmonology, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.

出版信息

Thorac Cardiovasc Surg. 2016 Apr;64(3):217-24. doi: 10.1055/s-0035-1548737. Epub 2015 Apr 14.

Abstract

BACKGROUND

Pericardial effusion (PE), atrial fibrillation (AF), and acute kidney injury (AKI) are commonly found after coronary artery surgery. These adverse events may also be interwoven in the postoperative period. In this prospective study, we investigated whether posterior pericardiotomy (PP) with intrapericardial tube positioned along the right atrium (pericardial space intervention) is effective in the prevention of these adverse events.

METHODS

The patients were randomly distributed to the study and control groups. The study group consisted of patients with pericardial space intervention, whereas the control group consisted of patients without pericardial space interventions. In all patients, a straight tube was placed in the anterior mediastinum and an angled tube was placed into the left hemithorax.

RESULTS

A total of 210 patients were studied: 107 in the control group and 103 in the study group. Statistically significant results were obtained in the amount of PE, cardiac tamponade, AF (p = 0.019), and AKI during the postoperative period, in favor of the study group. Length of hospital stay was significantly shorter in the study group (6.11 ± 2.31, p = 0.009).

CONCLUSION

The PP with intrapericardial tube approach is safe, easy, and effective in the prevention of PE, cardiac tamponade, and AF. The use of this approach may reduce the risk of developing AKI during the postoperative period. Besides, this technique also reduces the length of hospital stay.

摘要

背景

心包积液(PE)、心房颤动(AF)和急性肾损伤(AKI)在冠状动脉手术后很常见。这些不良事件在术后阶段也可能相互交织。在这项前瞻性研究中,我们调查了沿右心房放置心包内导管的后心包切开术(PP)(心包腔干预)在预防这些不良事件方面是否有效。

方法

将患者随机分为研究组和对照组。研究组由接受心包腔干预的患者组成,而对照组由未接受心包腔干预的患者组成。所有患者均在前纵隔放置一根直管,并在左半胸放置一根弯管。

结果

共研究了210例患者:对照组107例,研究组103例。术后阶段在PE量、心脏压塞、AF(p = 0.019)和AKI方面获得了具有统计学意义的结果,有利于研究组。研究组的住院时间明显更短(6.11 ± 2.31,p = 0.009)。

结论

采用心包内导管的PP方法在预防PE、心脏压塞和AF方面是安全、简便且有效的。使用这种方法可能会降低术后发生AKI的风险。此外,这项技术还缩短了住院时间。

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