一名接受腹膜透析患者的罗伦隐球菌性腹膜炎的成功治疗。
Successful treatment of Cryptococcus laurentii peritonitis in a patient on peritoneal dialysis.
作者信息
Asano Marina, Mizutani Makoto, Nagahara Yasuko, Inagaki Koji, Kariya Tetsuyoshi, Masamoto Daijiro, Urai Makoto, Kaneko Yukihiro, Ohno Hideaki, Miyazaki Yoshitsugu, Mizuno Masashi, Ito Yasuhiko
机构信息
Department of Nephrology, Handa Municipal Hospital, Japan.
出版信息
Intern Med. 2015;54(8):941-4. doi: 10.2169/internalmedicine.54.3586. Epub 2015 Apr 15.
A 32-year-old man on peritoneal dialysis (PD) was hospitalized for seven days due to fever. A diagnosis of yeast-like fungal peritonitis was made by Gram staining. The patient was started on intravenous micafungin and oral fluconazole therapy following removal of the PD catheter. A fungal pathogen was isolated from the peritoneal fluid and identified as Cryptococcus species. Based on antifungal susceptibility testing, the treatment was changed to voriconazole and continued for 3 months. A genetic analysis identified the isolate as Cryptococcus laurentii (C. laurentii). This patient was diagnosed with C. laurentii PD-related peritonitis and was successfully treated with voriconazole and removal of the PD catheter.
一名32岁接受腹膜透析（PD）的男性因发热住院7天。通过革兰氏染色诊断为酵母样真菌性腹膜炎。拔除PD导管后，患者开始接受静脉注射米卡芬净和口服氟康唑治疗。从腹膜液中分离出一种真菌病原体，鉴定为隐球菌属。根据抗真菌药敏试验，治疗改为伏立康唑，并持续3个月。基因分析确定该分离株为罗伦隐球菌（C. laurentii）。该患者被诊断为罗伦隐球菌相关性PD腹膜炎，并通过伏立康唑治疗和拔除PD导管成功治愈。
Zotero 插件