Xing Aijun, Ji Chunpeng, Shi Jihong, Du Xin, Huang Zhe, Lin Liming, Xiong Hailiang, Wu Shouling
Kailuan General Hospital, Tangshan 063000, China.
Graduate School, Hebei United University.
Zhonghua Liu Xing Bing Xue Za Zhi. 2015 Jan;36(1):40-4.
To investigate the relationship between ideal cardiovascular behaviors/factors and nonalcoholic fatty liver disease.
In our study, 54 303 workers who had participated in the 2006-2007 Kailuan health examination with complete data and without history of drinking, myocardial infarction, stroke or cancer, were recruited. All workers were under observation and their prevalence of nonalcoholic fatty liver disease recorded. According to the American Heart Association definition of ideal cardiovascular health behaviors and factors, multiple logistic regression method was used to calculate the OR and 95% CI for baseline behaviors and factors.
The prevalence of nonalcoholic fatty liver disease according to 0-1, 2, 3, 4, 5-7 ideal cardiovascular health behaviors/factors were 62.6% , 48.9% , 33.3% , 16.1% and 7.5% , respectively. Results from the logistic model showed that after adjustment for age, gender, income, education level and other confounders, the ideal cardiovascular health behaviors/factors were associated with nonalcoholic fatty liver disease and the ORs (95% CI) were reduced gradually with the increase of ideal cardiovascular health behaviors/factors, which were 1,0.61(0.56-0.66), 0.37(0.34-0.40), 0.17(0.15-0.18) and 0.08 (0.07-0.09), respectively, in the 2, 3, 4, 5-7 ideal behaviors/factors groups.
Ideal cardiovascular health behaviors and factors were associated with nonalcoholic fatty liver disease.
探讨理想心血管行为/因素与非酒精性脂肪性肝病之间的关系。
在我们的研究中，招募了54303名参加2006 - 2007年开滦健康体检、数据完整且无饮酒史、心肌梗死、中风或癌症病史的工人。对所有工人进行观察并记录其非酒精性脂肪性肝病的患病率。根据美国心脏协会对理想心血管健康行为和因素的定义，采用多因素logistic回归方法计算基线行为和因素的OR及95%CI。
根据0 - 1、2、3、4、5 - 7种理想心血管健康行为/因素，非酒精性脂肪性肝病的患病率分别为62.6%、48.9%、33.3%、16.1%和7.5%。logistic模型结果显示，在调整年龄、性别、收入、教育水平和其他混杂因素后，理想心血管健康行为/因素与非酒精性脂肪性肝病相关，且随着理想心血管健康行为/因素数量的增加，OR（95%CI）逐渐降低，在2、3、4、5 - 7种理想行为/因素组中，OR分别为1、0.61（0.56 - 0.66）、0.37（0.34 - 0.40）、0.17（0.15 - 0.18）和0.08（0.07 - 0.09）。
理想心血管健康行为和因素与非酒精性脂肪性肝病相关。
