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[一种钴(III)生物配合物的辐射防护特性]

[Radioprotective properties of a Co(III) biocomplex].

作者信息

Islamov Iu N, Akbarov A B, Khakimov P A, Shadieva N Kh, Islamov M N

出版信息

Radiobiologiia. 1989 Sep-Oct;29(5):644-7.

PMID:2587702
Abstract

In experiments with rats and mice irradiated with doses of 5 and 8.5 Gy respectively, the radioprotective properties of a coordination combination Co(III) with bioactive ligands have been investigated by the results of the hematological analysis, the indices of erythrocyte and leucocyte electric conductivity, average life, survival rate, and beta coefficient showing a probability of protecting the organism against fatal effect of ionizing radiation. The preparation has either therapeutic or protective action depending on the animal species and radiation dose.

摘要

在用分别为5 Gy和8.5 Gy剂量照射大鼠和小鼠的实验中,通过血液学分析结果、红细胞和白细胞电导率指标、平均寿命、存活率以及显示机体免受电离辐射致命影响概率的β系数,研究了具有生物活性配体的配位化合物Co(III)的辐射防护特性。该制剂根据动物种类和辐射剂量具有治疗或保护作用。

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