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用于人工膝关节生物力学体外试验台研究的快速成型:与钴铬合金植入材料的比较

Rapid prototyping for in vitro knee rig investigations of prosthetized knee biomechanics: comparison with cobalt-chromium alloy implant material.

作者信息

Schröder Christian, Steinbrück Arnd, Müller Tatjana, Woiczinski Matthias, Chevalier Yan, Weber Patrick, Müller Peter E, Jansson Volkmar

机构信息

Department of Orthopaedic Surgery, Physical Medicine and Rehabilitation, University Hospital of Munich (LMU), Campus Grosshadern, Marchioninistraße 15, 81377 Munich, Germany.

出版信息

Biomed Res Int. 2015;2015:185142. doi: 10.1155/2015/185142. Epub 2015 Mar 24.

Abstract

Retropatellar complications after total knee arthroplasty (TKA) such as anterior knee pain and subluxations might be related to altered patellofemoral biomechanics, in particular to trochlear design and femorotibial joint positioning. A method was developed to test femorotibial and patellofemoral joint modifications separately with 3D-rapid prototyped components for in vitro tests, but material differences may further influence results. This pilot study aims at validating the use of prostheses made of photopolymerized rapid prototype material (RPM) by measuring the sliding friction with a ring-on-disc setup as well as knee kinematics and retropatellar pressure on a knee rig. Cobalt-chromium alloy (standard prosthesis material, SPM) prostheses served as validation standard. Friction coefficients between these materials and polytetrafluoroethylene (PTFE) were additionally tested as this latter material is commonly used to protect pressure sensors in experiments. No statistical differences were found between friction coefficients of both materials to PTFE. UHMWPE shows higher friction coefficient at low axial loads for RPM, a difference that disappears at higher load. No measurable statistical differences were found in knee kinematics and retropatellar pressure distribution. This suggests that using polymer prototypes may be a valid alternative to original components for in vitro TKA studies and future investigations on knee biomechanics.

摘要

全膝关节置换术(TKA)后髌后并发症,如膝前疼痛和半脱位,可能与髌股生物力学改变有关,尤其是与滑车设计和股胫关节定位有关。已开发出一种方法,使用3D快速成型组件分别测试股胫关节和髌股关节的改良情况,用于体外测试,但材料差异可能会进一步影响结果。这项初步研究旨在通过在盘上环形装置测量滑动摩擦以及在膝关节试验台上测量膝关节运动学和髌后压力,来验证光聚合快速原型材料(RPM)制成的假体的使用。钴铬合金(标准假体材料,SPM)假体用作验证标准。此外,还测试了这些材料与聚四氟乙烯(PTFE)之间的摩擦系数,因为后一种材料通常用于在实验中保护压力传感器。两种材料与PTFE的摩擦系数之间未发现统计学差异。对于RPM,超高分子量聚乙烯(UHMWPE)在低轴向载荷下显示出更高的摩擦系数,这种差异在更高载荷下消失。在膝关节运动学和髌后压力分布方面未发现可测量的统计学差异。这表明,对于体外TKA研究和未来的膝关节生物力学研究,使用聚合物原型可能是替代原始组件的有效选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68c4/4388012/c80b41ea8cde/BMRI2015-185142.001.jpg

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