[The comparative effectiveness of beta-blockers and inhibitors of if-iodium using in patients with stable angina pectoris].

The purpose of the study was to evaluate the comparative effectiveness for using of different approaches to anti-ischemic therapy in patients with stable angina pectoris Class II-III. 90 patients with chronic form of ischemic heart disease that have been involved in present study along with nitrates, antiplatelet agents and statins received bisoprolol (Group I), carvedilol (Group II) and ivabradine (Group III). General clinical findings were analyzed as well as the results of diurnal ECG monitoring. As a result of treatment the number and duration of ischemic episodes reliably decreased in patients of all groups. The most effective and safe decrease in average daily heart rate was achieved in patients taking ivabradine. No statistically significant differences between values of investigated groups were revealed, that point out about comparable effects of antianginal action of bisoprolol, carvedilol and ivabradine.