de Moraes Augusto César Ferreira, Carvalho Heráclito Barbosa, Gomez-Martinez Sonia, Androutsos Odysseas, Jiménez-Pavón David, Sjöström Michael, Kafatos Anthony, Widhalm Kurt, Cañada David, Martin-Matillas Miguel, Beghin Laurent, Gottrand Frederic, Moreno Luis A
YCARE (Youth/Child and cARdiovascular Risk and Environmental) Research Group, Department of Preventive Medicine, School of Medicine of the University of São Paulo , São Paulo, SP , Brazil.
Blood Press. 2015;24(4):250-7. doi: 10.3109/08037051.2015.1033171. Epub 2015 Apr 16.
We aimed to estimate the attributable fraction of systolic (SBP) and diastolic blood pressure (DBP) that can be explained by family socioeconomic factors (FSFs) in adolescents using two observational studies.
Participants were recruited by multistage random cluster in two cross-sectional studies performed in Europe [Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study, n = 3308] and Brazil [Brazilian Cardiovascular Adolescent Health (BRACAH) study, n = 991]. SBP and DBP were measured, and FSFs (socioeconomic status and parental education) were self-reported in both studies. The correlations of SBP and DBP with FSFs were examined by multilevel linear regression through two different models (hierarchical and fully adjusted). The generalized attributable fractions of the FSFs were estimated by comparing the models.
Our results showed a significant inverse relationship between parental education (father and mother) and SBP in European boys. The higher generalized attributable fraction to SBP was observed in boys (13.2-22.4%). In girls, we found lower generalized attributable fractions to DBP (10.8-12.1% in Brazilian girls and 3.1-3.8% in European girls).
Our findings revealed a significant inverse relationship between parental education and SBP in European boys. FSF also significantly influenced blood pressure in adolescents, mainly in Brazilian adolescents.
我们旨在通过两项观察性研究,估计青少年中可由家庭社会经济因素(FSFs)解释的收缩压(SBP)和舒张压(DBP)的归因分数。
在欧洲[青少年营养促进欧洲健康生活方式(HELENA)研究,n = 3308]和巴西[巴西青少年心血管健康(BRACAH)研究,n = 991]进行的两项横断面研究中,通过多阶段随机整群抽样招募参与者。在两项研究中均测量了SBP和DBP,并让参与者自行报告FSFs(社会经济地位和父母教育程度)。通过两种不同模型(分层模型和完全调整模型)的多水平线性回归,检验SBP和DBP与FSFs之间的相关性。通过比较模型估计FSFs的广义归因分数。
我们的结果显示,在欧洲男孩中,父母教育程度(父亲和母亲)与SBP之间存在显著的负相关关系。在男孩中观察到SBP的广义归因分数更高(13.2 - 22.4%)。在女孩中,我们发现DBP的广义归因分数较低(巴西女孩为10.8 - 12.1%,欧洲女孩为3.1 - 3.8%)。
我们的研究结果显示,在欧洲男孩中,父母教育程度与SBP之间存在显著的负相关关系。FSFs也对青少年的血压有显著影响,主要是在巴西青少年中。