de Moraes Augusto César Ferreira, Bel-Serrat Silvia, Manios Yannis, Molnar Dénes, Kafatos Anthony, Cuenca-García Magdalena, Huybrechts Inge, Sette Stefania, Widhalm Kurt, Stehle Peter, Jiménez-Pavón David, Carvalho Heráclito Barbosa, Moreno Luis A
1 Department of Preventive Medicine, School of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, Brazil 2 GENUD-Growth, Exercise, Nutrition and Development, University of Zaragoza, Zaragoza, Spain 3 School of Health Sciences of the University of Zaragoza, Zaragoza, Spain 4 YCARE (Youth/Child and cArdiovascular Risk and Environmental) Research Group, FMUSP, São Paulo, SP, Brazil
2 GENUD-Growth, Exercise, Nutrition and Development, University of Zaragoza, Zaragoza, Spain 3 School of Health Sciences of the University of Zaragoza, Zaragoza, Spain.
Eur J Public Health. 2015 Jun;25(3):450-6. doi: 10.1093/eurpub/cku233. Epub 2015 Jan 24.
To analyze the association between dietary protein and amino acids intake and systolic (SBP) and diastolic (DBP) blood pressure in European adolescents.
Participants were from the cross-sectional study performed in Europe, Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA study; n = 1605; 12.5-17.5 years; 833 girls) selected by complex sampling. The associations between dietary protein and amino acids intake and SBP/DBP were examined by multilevel linear regression models (context variable by school); the analysis being stratified by sex. Cities, seasonality, age, socioeconomic level, parental education level, body mass index, waist circumference, Tanner stage and physical activity were used as covariates.
In boys, we found an inverse association between protein (animal and vegetable) intake and DBP; and a positive association between histidine and SBP. In girls, we observed a positive association among tryptophan, histidine with SBP and methionine with DBP. On the other hand, we observed an inverse association between tyrosine and both SBP and DBP levels in girls.
The association between amino acids and BP levels is controversial and depends on the type of amino acids, and protein intake can help control the DBP in boys.
分析欧洲青少年膳食蛋白质和氨基酸摄入量与收缩压(SBP)和舒张压(DBP)之间的关联。
参与者来自在欧洲进行的一项横断面研究,即欧洲青少年营养健康生活方式研究(HELENA研究;n = 1605;12.5 - 17.5岁;833名女孩),采用复杂抽样方法选取。通过多水平线性回归模型(以学校为背景变量)检验膳食蛋白质和氨基酸摄入量与收缩压/舒张压之间的关联;分析按性别分层。将城市、季节、年龄、社会经济水平、父母教育水平、体重指数、腰围、坦纳分期和身体活动作为协变量。
在男孩中,我们发现蛋白质(动物蛋白和植物蛋白)摄入量与舒张压呈负相关;组氨酸与收缩压呈正相关。在女孩中,我们观察到色氨酸、组氨酸与收缩压以及蛋氨酸与舒张压之间呈正相关。另一方面,我们观察到酪氨酸与女孩的收缩压和舒张压水平均呈负相关。
氨基酸与血压水平之间的关联存在争议,且取决于氨基酸的类型,蛋白质摄入有助于控制男孩的舒张压。