Khlystov V Iu, Kunel'skaia N L, Kriukov A I, Maleva I P, Poliakova T S
Vestn Otorinolaringol. 1989 Sep-Oct(5):5-8.
Seventy eight chronic alcoholics, aged 19 to 50 years, were exposed to audiologic and rheoencephalographic examinations. Tone hearing impairment was found in all subjects. The recruitment or greater than normal increment of loudness was primarily identified in patients of Group 1 that comprised those who consumed alcohol from 1 to 10 years. Rheoencephalographic examinations showed decreases of the rheographic index as well as the tone of large and medium caliber arteries in all patients. Group 2 patients who consumed alcohol for more than 10 years displayed greater changes in the vessel tone than Group 1 patients. Analysis of rheoencephalographic waves demonstrated that peripheral and venous tone was decreased in Group 1 patients and increased in Group 2 alcoholics. Visual analysis of rheoencephalographic waves showed lability in the vessel tone of Group 1 patients and a trend for a vessel spasm in Group 2 patients. The results give evidence that Group 1 chronic alcoholics develop toxic lesions of receptors of the hearing organ which is confirmed by the occurrence of recruitment, sound perception impairment, close to normal speech discrimination and insignificant changes in cerebral hemodynamics. Group 2 alcoholics develop marked disorders in cerebral hemodynamics leading to changes in central and intermediate compartments of the hearing organ.
78名年龄在19至50岁之间的慢性酗酒者接受了听力和脑血流图检查。所有受试者均发现有纯音听力损害。响度重振或大于正常响度增量主要在第1组患者中发现，该组患者饮酒1至10年。脑血流图检查显示所有患者的血流图指数以及大中口径动脉的张力均降低。饮酒超过10年的第2组患者的血管张力变化比第1组患者更大。脑血流图波形分析表明，第1组患者的外周和静脉张力降低，第2组酗酒者则升高。脑血流图波形的视觉分析显示，第1组患者的血管张力不稳定，第2组患者有血管痉挛的趋势。结果表明，第1组慢性酗酒者发生了听觉器官受体的中毒性损害，这通过重振的出现、声音感知损害、接近正常的言语辨别以及脑血流动力学的微小变化得到证实。第2组酗酒者脑血流动力学出现明显紊乱，导致听觉器官的中枢和中间部分发生变化。
