Unit of Endocrinology, Theagenio Hospital, Aristotle University of Thessaloniki, Greece.
Department of Endocrinology, Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, UK.
Hormones (Athens). 2015 Jan-Mar;14(1):70-80. doi: 10.1007/BF03401382.
The pituitary gland is significantly affected during gestation in terms of both size and function. Due to this physiologic adaptation, endocrine evaluation and interpretation of imaging is far more complex than in the non-pregnant state. Pituitary disorders are rare in pregnancy, as they are usually associated with gonadal dysfunction, thereby posing difficulties with fertility. This review will focus on pituitary adenomas (prolactinomas, GH-secreting and ACTH-secreting), their diagnostic handicaps and the recommendations for treatment. We will also discuss the two pituitary disorders encountered in pregnancy, Sheehan's syndrome and lymphocytic hypophysitis.
垂体在妊娠期间无论在大小还是功能上都受到显著影响。由于这种生理适应,内分泌评估和影像学解读比非妊娠状态复杂得多。在妊娠期间,垂体疾病很少见,因为它们通常与性腺功能障碍有关,从而导致生育困难。本综述将重点介绍垂体腺瘤(催乳素瘤、GH 分泌瘤和 ACTH 分泌瘤)及其诊断障碍,以及治疗建议。我们还将讨论妊娠期间遇到的两种垂体疾病,希恩氏综合征和淋巴细胞性垂体炎。