Nosaka Nobuyuki, Ichiba Shingo, Tsukahara Kohei, Knaup Emily, Hayashi Kumiko, Kasahara Shingo, Kobayashi Yoshinori, Oka Makio, Kobayashi Katsuhiro, Yoshinaga Harumi, Ujike Yoshihito
Advanced Emergency and Critical Care Medical Center, Okayama University Hospital, Okayama, Japan.
Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
BMC Pediatr. 2015 Apr 1;15:29. doi: 10.1186/s12887-015-0348-1.
Extracorporeal membrane oxygenation (ECMO) is now a candidate therapy for children with acute respiratory failure.
We report our experience of using central ECMO therapy for acute respiratory distress syndrome followed by seizure in a 15-month-old girl with a severe epileptic disorder. Her respiratory distress was refractory to standard medical treatment and mechanical ventilatory support. Her condition was complicated by development of a pneumothorax. The patient was successfully weaned off ECMO and discharged without deterioration of her neurological status.
The successful outcome in this case resulted from the central ECMO, which enabled "lung rest" and adequate cerebral blood flow. In skilled ECMO facilities, early implementation of ECMO would give some advantages to patients such as the one presented here. Given the invasiveness and the ease of the procedure, introduction of dual-lumen catheters adequately sized for pediatric patients in Japan is required.
体外膜肺氧合(ECMO)现已成为急性呼吸衰竭儿童的一种候选治疗方法。
我们报告了对一名患有严重癫痫疾病的15个月大女孩使用中心ECMO治疗急性呼吸窘迫综合征后继发癫痫发作的经验。她的呼吸窘迫对标准药物治疗和机械通气支持无效。她的病情因气胸的发展而复杂化。患者成功撤机,出院时神经状态未恶化。
该病例的成功结果得益于中心ECMO,它实现了“肺休息”并保证了充足的脑血流量。在技术熟练的ECMO治疗机构中,早期实施ECMO会给像本文所述这样的患者带来一些益处。鉴于该操作的侵入性和简便性,在日本需要引入尺寸适合儿科患者的双腔导管。