Shu Min, Zhang Yi Qiong, Li Zhiyao, Liu Guan J, Wan Chaomin, Wen Yang
Department of Pediatrics, West China Second University Hospital, West China Women's and Children's Hospital, No. 17, Section Three, Ren Min Nan Lu Avenue, Chengdu, Sichuan, China, 610041.
Cochrane Database Syst Rev. 2015 Apr 18;2015(4):CD008578. doi: 10.1002/14651858.CD008578.pub3.
Mumps is an infectious disease caused by the mumps virus. Chinese physicians generally believe that Chinese medicinal herbs are effective in alleviating symptoms and reducing the duration of mumps. Herbalists tend to develop a treatment plan according to the individual's symptoms.
To evaluate the effectiveness and safety of Chinese medicinal herbs combined with routine treatments for mumps.
We searched CENTRAL (2015, Issue 1), MEDLINE (1948 to January week 4, 2015), EMBASE (1974 to February 2015), CINAHL (1981 to February 2015), AMED (1985 to April 2014), the Chinese Biomedical Database (CBM) (1980 to February 2015), China National Knowledge Infrastructure (CNKI) (1979 to February 2015), VIP Information (1989 to February 2015), and relevant databases of ongoing trials.
Randomised controlled trials (RCTs) of Chinese medicinal herbs for mumps (with or without complications).
Two review authors independently evaluated trial quality and conducted data extraction. We contacted the trial authors for missing data regarding participant allocation. Some trials allocated participants according to the participants' admission sequence, making it a pseudo-random allocation. None of the trials concealed participants' allocation or used blinding.
We did not identify any eligible trials for inclusion. We identified 108 studies that claimed to use random allocation. We excluded 104 studies because the allocation methods the authors had used were not actually randomised. We were unable to contact the trial authors of the remaining four studies. These trials require further evaluation and have been allocated to the 'Studies awaiting classification' section.
AUTHORS' CONCLUSIONS: We did not find any RCTs for or against Chinese herbal medicine used in the treatment of mumps. We hope more high-quality RCTs will be conducted in the future.
腮腺炎是由腮腺炎病毒引起的一种传染病。中国医生普遍认为中药在缓解腮腺炎症状和缩短病程方面有效。中医师倾向于根据个体症状制定治疗方案。
评估中药联合常规治疗对腮腺炎的有效性和安全性。
我们检索了Cochrane系统评价数据库(2015年第1期)、医学索引数据库(1948年至2015年1月第4周)、荷兰医学文摘数据库(1974年至2015年2月)、护理学与健康领域数据库(1981年至2015年2月)、联合和补充医学数据库(1985年至2014年4月)、中国生物医学文献数据库(1980年至2015年2月)、中国知网(1979年至2015年2月)、维普资讯(1989年至2015年2月)以及正在进行试验的相关数据库。
关于中药治疗腮腺炎(有无并发症)的随机对照试验。
两位综述作者独立评估试验质量并进行数据提取。我们就参与者分配的缺失数据联系了试验作者。一些试验根据参与者的入院顺序分配参与者,这属于伪随机分配。没有一项试验对参与者分配情况进行隐藏或采用盲法。
我们未找到任何符合纳入标准的试验。我们识别出108项声称采用随机分配的研究。我们排除了104项研究,因为作者所使用的分配方法并非真正随机。我们无法联系到其余四项研究的试验作者。这些试验需要进一步评估,已被归入“待分类研究”部分。
我们未找到支持或反对使用中药治疗腮腺炎的随机对照试验。我们希望未来能开展更多高质量的随机对照试验。