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Acetylcholine receptor antibody in myasthenia gravis.

作者信息

Marchiori P E, dos Reis M, Quevedo M E, Scaff M, Cossermelli W, Assis J L, de Oliveira R M

机构信息

Department of Neurology, São Paulo University Medical School, Brazil.

出版信息

Acta Neurol Scand. 1989 Nov;80(5):387-9. doi: 10.1111/j.1600-0404.1989.tb03898.x.

Abstract

Radioimmunoassay techniques were used to detect antibodies to the acetylcholine receptor (AAChR) in 164 patients with adult-onset myasthenia gravis. AAChR levels above 0.6 nM/l were considered pathological and were found in 67% of the patients with an average value of 58.99 +/- 125.02 nM/l (0.6-900.0). Correlation, with clinical functional status, the histopathological thymus alterations and the different therapeutics used did not disclose any statistically significant differences.

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