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重复经颅磁刺激用于中风后上肢运动功能恢复

Repetitive transcranial magnetic stimulation for motor recovery of the upper limb after stroke.

作者信息

Lüdemann-Podubecká Jitka, Bösl Kathrin, Nowak Dennis Alexander

机构信息

HELIOS Klinik Kipfenberg, Kipfenberg, Germany.

HELIOS Klinik Kipfenberg, Kipfenberg, Germany.

出版信息

Prog Brain Res. 2015;218:281-311. doi: 10.1016/bs.pbr.2014.12.001. Epub 2015 Apr 4.

DOI:10.1016/bs.pbr.2014.12.001
PMID:25890143
Abstract

OBJECTIVE

Repetitive transcranial magnetic stimulation changes excitability of the motor cortex and it has hereby the potential to modulate changes in neural processing which impede motor recovery after stroke.

METHODS

This chapter presents an up-to-day systematic review of the treatment effects of repetitive transcranial magnetic stimulation (rTMS) in promoting motor recovery of the affected upper limb after stroke.

RESULTS

Thirty-seven trials were included in the analysis. The selected studies involved a total of 871 stroke subjects. All stimulation protocols pride on interhemispheric imbalance model.

INTERPRETATION

rTMS enhances motor recovery of the affected hand after stroke; however, the data available until today is too limited to support its routine use.

摘要

目的

重复经颅磁刺激可改变运动皮层的兴奋性,因此有潜力调节阻碍中风后运动恢复的神经加工变化。

方法

本章对重复经颅磁刺激(rTMS)促进中风后患侧上肢运动恢复的治疗效果进行了最新的系统评价。

结果

分析纳入了37项试验。所选研究共涉及871名中风患者。所有刺激方案均基于半球间失衡模型。

解读

rTMS可增强中风后患侧手的运动恢复;然而,目前可得的数据过于有限,无法支持其常规使用。

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