Debi U, Thulkar S, Sharma S, Sharma M C, Seenu V, Deo S V S, Agarwal S, Hari S
Postgraduate Institute of Medical Education and Research, Department of Superspeciality of Gastroenterology, Division of GE Radiology, Chandigarh (UT) -160 012 India.
Malays J Pathol. 2015 Apr;37(1):25-33.
Among percutaneous biopsy techniques, the vacuum assisted breast biopsy (VAB) obtains large tissue samples to alleviate some of the limitations associated with conventional percutaneous biopsy techniques. We aimed to determine the efficacy of VAB in previous equivocal biopsies using the mammotome device.
A prospective non-randomized efficacy study was planned and executed on 43 patients (42 women, 1 man) whose previous FNAC and/or CNB of breast masses yielded inconclusive results or were suspicious for cancer.
VAB revealed malignancy in 31 (72%) of the 43 patients. Among them, 23 were diagnosed as infiltrative ductal carcinoma (IDC) on VAB, 20 underwent surgery and the final histopathological diagnosis was the same in 19 of them. One patient showed ductal carcinoma-in-situ (DCIS) only in the surgical specimen. Other malignancies included infiltrating lobular carcinoma (ILC) in 5 patients and one each of DCIS, non- Hodgkin lymphoma (NHL) and metastasis from lung cancer. Benign lesions were detected in 12 (28%) patients. These included 8 fibroadenomas, 2 fibrocystic disease and 1 each of mastitis and breast abscess. Four patients with fibroadenoma underwent surgical excision.
在经皮活检技术中，真空辅助乳腺活检（VAB）可获取较大的组织样本，以缓解一些与传统经皮活检技术相关的局限性。我们旨在确定使用麦默通设备进行的VAB在既往诊断不明确的活检中的有效性。
对43例患者（42名女性，1名男性）进行了一项前瞻性非随机有效性研究，这些患者既往对乳腺肿块进行细针穿刺抽吸活检（FNAC）和/或粗针穿刺活检（CNB）的结果不明确或怀疑为癌症。
VAB显示43例患者中有31例（72%）为恶性。其中，23例在VAB中被诊断为浸润性导管癌（IDC），20例接受了手术，其中19例最终组织病理学诊断相同。1例患者仅在手术标本中显示导管原位癌（DCIS）。其他恶性肿瘤包括5例浸润性小叶癌（ILC）、1例DCIS、1例非霍奇金淋巴瘤（NHL）和1例肺癌转移。12例（28%）患者检测到良性病变。其中包括8例纤维腺瘤、2例纤维囊性疾病、1例乳腺炎和1例乳腺脓肿。4例纤维腺瘤患者接受了手术切除。
