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中国重症精神疾病患者功能水平的预测因素:一项为期12个月的前瞻性队列研究。

Predictors of levels of functioning among Chinese people with severe mental illness: a 12-month prospective cohort study.

作者信息

Chien Wai-Tong, Lam Claire K K, Ng Bacon F L

机构信息

School of Nursing, Faculty of Health & Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China.

Chinese Medicine Department, Hospital Authority Hong Kong, Lok Fu, Hong Kong SAR, China.

出版信息

J Clin Nurs. 2015 Jul;24(13-14):1860-73. doi: 10.1111/jocn.12843. Epub 2015 Apr 20.

Abstract

AIM AND OBJECTIVES

The aim of the study was to identify the predictors of functioning in Chinese people with serious mental illness.

BACKGROUND

Mental healthcare services for people suffering from serious mental illness are delivered to not only minimise their psychiatric symptoms but also enhance their levels of functioning in the community. Yet, there is insufficient research directed towards the associated or predictive factors that may influence different aspects of functioning, particularly in terms of patients' psychosocial variables.

DESIGN

A longitudinal, prospective cohort study design was adopted.

METHODS

A clustered random sample of 395 of 611 outpatients with serious mental illness completed the same set of questionnaires at baseline and at 12 months. Changes in patients' functioning as measured by self-maintenance, social functioning and community living skills were recorded over 12 months. Potential relationships between their level of functioning and symptom severity, self-esteem, self-efficacy, perceived negative familial response, negative self-stigma towards mental illness, re-hospitalisation rate and socio-demographic characteristics were investigated.

RESULTS

Most participants reported moderate to moderately high levels of overall functioning, self-efficacy, self-stigma and perceived negative familial response at baseline and there were significant observed correlations between these variables. Results of multiple regression models indicated that while symptom severity predicted functioning in patients with psychotic and affective disorders, a negatively perceived familial response only predicted negative changes in social functioning of the patients with psychotic disorders (β = -0·25). In addition, improvements in self-efficacy (β = 0·23) and reduction in self-stigma (β = -0·15) positively predicted changes in the community living skills of patients with affective disorders.

CONCLUSION

The findings indicate the significance of psychiatric patients' symptom management and factors such as self-efficacy and self-stigma to predict their functioning over a 12-month follow-up.

RELEVANCE TO CLINICAL PRACTICE

Mental healthcare services should consider giving priority to self-stigma reduction and empowerment to manage illness especially in this population of patients and their families, thus effectively enhancing their self-care ability to cope with their illness and/or difficult life situations.

摘要

目的与目标

本研究的目的是确定中国重症精神疾病患者功能状况的预测因素。

背景

为重症精神疾病患者提供精神卫生保健服务,不仅是为了尽量减轻他们的精神症状,也是为了提高他们在社区中的功能水平。然而,针对可能影响功能不同方面的相关因素或预测因素的研究不足,特别是在患者心理社会变量方面。

设计

采用纵向、前瞻性队列研究设计。

方法

从611名重症精神疾病门诊患者中抽取395名进行整群随机抽样,这些患者在基线和12个月时完成了同一套问卷。记录患者在12个月内自我维持、社会功能和社区生活技能方面功能的变化。研究了他们的功能水平与症状严重程度、自尊、自我效能感、感知到的家庭负面反应、对精神疾病的负面自我污名、再住院率和社会人口学特征之间的潜在关系。

结果

大多数参与者在基线时报告总体功能、自我效能感、自我污名和感知到的家庭负面反应处于中度至中度偏高水平,并且这些变量之间存在显著的相关性。多元回归模型结果表明,虽然症状严重程度可预测精神病性和情感性障碍患者的功能状况,但负面的家庭反应感知仅能预测精神病性障碍患者社会功能的负面变化(β=-0.25)。此外,自我效能感的提高(β=0.23)和自我污名的降低(β=-0.15)可正向预测情感性障碍患者社区生活技能的变化。

结论

研究结果表明,在12个月的随访中,精神病患者的症状管理以及自我效能感和自我污名等因素对于预测其功能状况具有重要意义。

与临床实践的相关性

精神卫生保健服务应考虑优先减少自我污名并增强应对疾病的能力,尤其是在这类患者及其家庭中,从而有效提高他们应对疾病和/或困难生活状况的自我护理能力。

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