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芬太尼透皮贴剂熬煮法——一种新型阿片类药物滥用方法。

The Fentanyl Patch Boil-Up - A Novel Method of Opioid Abuse.

作者信息

Schauer Cameron K M W, Shand James A D, Reynolds Thomas M

机构信息

Department of General Medicine, Whangarei Hospital, Whangarei, New Zealand.

Emergency Medicine Department, Whangarei Hospital, Whangarei, New Zealand.

出版信息

Basic Clin Pharmacol Toxicol. 2015 Nov;117(5):358-9. doi: 10.1111/bcpt.12412. Epub 2015 May 9.

Abstract

Fentanyl is a potent opioid analgesic used in the treatment of pain. Transdermal fentanyl patches are now widely utilized as an acceptable and efficacious method of medication delivery. Unfortunately, the potential for their abuse is well recognized. Previous case reports have documented deaths after intravenous (IV) misuse of fentanyl which had been extracted from Duragesic (liquid reservoir type) patches. We present a case of IV fentanyl abuse after the extraction from a Mylan (matrix type) patch. This method of abuse has not previously been described in the literature.

摘要

芬太尼是一种强效阿片类镇痛药,用于治疗疼痛。透皮芬太尼贴剂目前被广泛用作一种可接受且有效的给药方法。不幸的是,其被滥用的可能性已得到充分认识。既往病例报告记录了静脉内(IV)滥用从多瑞吉(液体储库型)贴剂中提取的芬太尼后导致的死亡案例。我们报告一例从迈兰(基质型)贴剂中提取后静脉内滥用芬太尼的病例。这种滥用方法此前在文献中尚未有描述。

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