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1型神经纤维瘤病患者转移性黑色素瘤的侵袭性行为

Aggressive behaviour of metastatic melanoma in a patient with neurofibromatosis type 1.

作者信息

Foley Robert W, Maweni Robert M, Fabre Aurelie, Healy David G

机构信息

School of Medicine and Medical Science, University College Dublin, Belfield, Dublin 4, Ireland ; Conway Institute of Biomedical and Biomolecular Research, University College Dublin, Belfield, Dublin 4, Ireland.

School of Medicine and Medical Science, University College Dublin, Belfield, Dublin 4, Ireland.

出版信息

Case Rep Surg. 2015;2015:431943. doi: 10.1155/2015/431943. Epub 2015 Mar 29.

DOI:10.1155/2015/431943
PMID:25893129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4393914/
Abstract

Malignant melanoma is a common skin neoplasm bearing poor prognosis when presenting with metastases. Rarely melanoma metastases present without an identifiable primary cutaneous lesion despite exhaustive workup. We describe the case of a solitary lung metastasis in a patient with neurofibromatosis type 1 without an identifiable primary tumour. The rapid progression of this malignant neoplasm that led to the patient's death within 1 year is described.

摘要

恶性黑色素瘤是一种常见的皮肤肿瘤，出现转移时预后较差。尽管进行了详尽的检查，但黑色素瘤转移灶罕见地在没有可识别的原发性皮肤病变的情况下出现。我们描述了一例1型神经纤维瘤病患者出现孤立性肺转移且无可识别的原发性肿瘤的病例。本文描述了这种恶性肿瘤的快速进展，该患者在1年内死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af4d/4393914/3b92d0f3263c/CRIS2015-431943.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af4d/4393914/28ccf22102f7/CRIS2015-431943.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af4d/4393914/1c507036df20/CRIS2015-431943.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af4d/4393914/a07b984c5b79/CRIS2015-431943.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af4d/4393914/3b92d0f3263c/CRIS2015-431943.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af4d/4393914/28ccf22102f7/CRIS2015-431943.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af4d/4393914/1c507036df20/CRIS2015-431943.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af4d/4393914/a07b984c5b79/CRIS2015-431943.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af4d/4393914/3b92d0f3263c/CRIS2015-431943.004.jpg

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A resected melanoma of the lung metastasized from an occult skin lesion: a case report.一例隐匿性皮肤病变转移所致的肺切除黑色素瘤：病例报告
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不明原发灶黑色素瘤：荷兰的一项基于人群的研究。
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