Quilici Giacomo, Berardi Andrea, Gaudesi Davide, Gourlay Louise J, Bolognesi Martino, Musco Giovanna
Biomolecular NMR Unit, c/o S. Raffaele Scientific Institute, Via Olgettina, 58, Milan, Italy.
Department of Biosciences, University of Milan, Via Celoria, 26, 20133, Milan, Italy.
Biomol NMR Assign. 2015 Oct;9(2):347-50. doi: 10.1007/s12104-015-9607-1. Epub 2015 Apr 19.
BPSL1445 is a lipoprotein produced by the Gram-negative bacterium Burkholderia pseudomallei (B. pseudomallei), the etiological agent of melioidosis. Immunodetection assays against sera patients using protein microarray suggest BPSL1445 involvement in melioidosis. Herein we report backbone, side chain NMR assignment and secondary structure for the recombinant protein.
BPSL1445是由革兰氏阴性菌类鼻疽伯克霍尔德菌（类鼻疽伯克霍尔德菌）产生的一种脂蛋白，类鼻疽伯克霍尔德菌是类鼻疽的病原体。使用蛋白质微阵列针对患者血清进行的免疫检测分析表明BPSL1445与类鼻疽有关。在此我们报告了重组蛋白的主链、侧链核磁共振归属及二级结构。
