维生素D受体多态性及其对血钙正常的甲状旁腺功能亢进患者骨密度的影响。 - Suppr

Polymorphisms of the vitamin D receptor and their effect on bone mass density in patients with normocalcemic hyperparathyroidism.

作者信息

Castrillón Jose Luis Perez, Díaz-Soto Gonzalo, Jauregui Olatz Izaola, Romero Enrique, de Luis Román Daniel

机构信息

Internal Medicine Service, Hospital Rio Hortega, IEN-University of Valladolid, Calle Dulzaina 2, 47012, Valladolid, Spain.

Center of Investigation of Endocrinology and Nutrition Medicine School, IEN-University of Valladolid, Valladolid, Spain.

出版信息

Endocrine. 2015 Dec;50(3):816-8. doi: 10.1007/s12020-015-0611-0. Epub 2015 Apr 21.

DOI:10.1007/s12020-015-0611-0

PMID:25896554

Abstract

摘要

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Polymorphisms of the vitamin D receptor and their effect on bone mass density in patients with normocalcemic hyperparathyroidism.维生素D受体多态性及其对血钙正常的甲状旁腺功能亢进患者骨密度的影响。

Endocrine. 2015 Dec;50(3):816-8. doi: 10.1007/s12020-015-0611-0. Epub 2015 Apr 21.

Clinical Expression of Calcium Sensing Receptor Polymorphism (A986S) in Normocalcemic and Asymptomatic Hyperparathyroidism.钙敏感受体多态性（A986S）在血钙正常和无症状性甲状旁腺功能亢进中的临床表达

Horm Metab Res. 2016 Mar;48(3):163-168. doi: 10.1055/s-0035-1559723. Epub 2015 Sep 2.

Vitamin D receptor polymorphisms as a determinant of bone mass and PTH secretion: from facts to controversies.维生素D受体基因多态性作为骨量和甲状旁腺激素分泌的决定因素：从事实到争议

Nephrol Dial Transplant. 1999 May;14(5):1066-8. doi: 10.1093/ndt/14.5.1066.

Of bone and genes: vitamin D receptor polymorphism and primary hyperparathyroidism.骨骼与基因：维生素D受体多态性与原发性甲状旁腺功能亢进症

Eur J Endocrinol. 1996 Jun;134(6):685-6. doi: 10.1530/eje.0.1340685.

The vitamin D receptor (VDR) start codon polymorphism in primary hyperparathyroidism and parathyroid VDR messenger ribonucleic acid levels.原发性甲状旁腺功能亢进症中维生素D受体（VDR）起始密码子多态性与甲状旁腺VDR信使核糖核酸水平

J Clin Endocrinol Metab. 1999 May;84(5):1690-4. doi: 10.1210/jcem.84.5.5707.

Influence of Bsml vitamin D receptor gene polymorphism on the response to a single bolus of calcitrol in hemodialysis patients.Bsml维生素D受体基因多态性对血液透析患者单次推注骨化三醇反应的影响。

Clin Nephrol. 2001 Aug;56(2):111-6.

Vitamin D receptor gene polymorphisms and bone mineral density in patients on hemodialysis.血液透析患者维生素D受体基因多态性与骨密度

Nephron. 2000 Apr;84(4):381-2. doi: 10.1159/000045617.

The effects of vitamin D receptor polymorphism on secondary hyperparathyroidism and bone density after renal transplantation.维生素D受体基因多态性对肾移植术后继发性甲状旁腺功能亢进及骨密度的影响。

J Bone Miner Res. 2002 Oct;17(10):1768-73. doi: 10.1359/jbmr.2002.17.10.1768.

Vitamin D receptor polymorphisms correlate to parathyroid cell function in primary hyperparathyroidism.

J Clin Endocrinol Metab. 1997 Jun;82(6):1772-5. doi: 10.1210/jcem.82.6.4012.

Low bone mineral density and vitamin d deficiency correlated with genetics and other bone markers in female Turkish immigrants in Germany.在德国的土耳其女性移民中，低骨矿物质密度和维生素D缺乏与遗传因素及其他骨标志物相关。

Clin Rheumatol. 2016 Nov;35(11):2789-2795. doi: 10.1007/s10067-016-3237-6. Epub 2016 Mar 31.

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Bone Turnover Markers: Basic Biology to Clinical Applications.骨转换标志物：基础生物学与临床应用。

Endocr Rev. 2023 May 8;44(3):417-473. doi: 10.1210/endrev/bnac031.

Impact of vitamin D receptor polymorphisms in centenarians.维生素D受体基因多态性对百岁老人的影响。

Endocrine. 2016 Aug;53(2):558-64. doi: 10.1007/s12020-016-0908-7. Epub 2016 Mar 8.

本文引用的文献

Normocalcemic primary hyperparathyroidism: a newly emerging disease needing therapeutic intervention.血钙正常的原发性甲状旁腺功能亢进症：一种需要治疗干预的新出现的疾病。

Hormones (Athens). 2012 Oct-Dec;11(4):390-6. doi: 10.14310/horm.2002.1370.

1,25-dihydroxyvitamin D and the vitamin D receptor gene polymorphism Apa1 influence bone mineral density in primary hyperparathyroidism.1,25-二羟维生素 D 和维生素 D 受体基因多态性 Apa1 影响原发性甲状旁腺功能亢进症患者的骨密度。

PLoS One. 2013;8(2):e56019. doi: 10.1371/journal.pone.0056019. Epub 2013 Feb 13.

Normocalcemic primary hyperparathyroidism.血钙正常型原发性甲状旁腺功能亢进症。

J Clin Densitom. 2013 Jan-Mar;16(1):33-9. doi: 10.1016/j.jocd.2012.12.001.

Bone turnover markers in primary hyperparathyroidism.原发性甲状旁腺功能亢进症中的骨转换标志物。

J Clin Densitom. 2013 Jan-Mar;16(1):22-7. doi: 10.1016/j.jocd.2012.11.004.

Involvement of α-klotho, fibroblast growth factor-, vitamin-D- and calcium-sensing receptor in 53 patients with primary hyperparathyroidism.α-klotho、成纤维细胞生长因子、维生素 D 和钙敏感受体在 53 例原发性甲状旁腺功能亢进症患者中的作用。

Endocrine. 2013 Aug;44(1):255-63. doi: 10.1007/s12020-013-9881-6. Epub 2013 Jan 20.

Normocalcemic primary hyperparathyroidism: one-year follow-up in one hundred postmenopausal women.血钙正常的原发性甲状旁腺功能亢进症：100名绝经后女性的一年随访

Endocrine. 2012 Dec;42(3):764-6. doi: 10.1007/s12020-012-9694-z.

"Single nucleotide polymorphisms of the OPG/RANKL system genes in primary hyperparathyroidism and their relationship with bone mineral density"."原发性甲状旁腺功能亢进症中 OPG/RANKL 系统基因的单核苷酸多态性及其与骨密度的关系"。

BMC Med Genet. 2011 Dec 20;12:168. doi: 10.1186/1471-2350-12-168.

Catabolic and anabolic actions of parathyroid hormone on the skeleton.甲状旁腺激素对骨骼的分解代谢和合成代谢作用。

J Endocrinol Invest. 2011 Nov;34(10):801-10. doi: 10.3275/7925. Epub 2011 Sep 23.

Increased fracture risk in normocalcemic postmenopausal women with high parathyroid hormone levels: a 16-year follow-up study.甲状旁腺激素水平升高的血钙正常绝经后妇女骨折风险增加：一项 16 年随访研究。

Calcif Tissue Int. 2011 Mar;88(3):238-45. doi: 10.1007/s00223-010-9454-0. Epub 2010 Dec 23.

The role of the receptor activator of nuclear factor-kappaB ligand/osteoprotegerin cytokine system in primary hyperparathyroidism.核因子-κB受体活化因子配体/骨保护素细胞因子系统在原发性甲状旁腺功能亢进症中的作用

J Clin Endocrinol Metab. 2008 Mar;93(3):967-73. doi: 10.1210/jc.2007-1645. Epub 2007 Dec 11.

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Polymorphisms of the vitamin D receptor and their effect on bone mass density in patients with normocalcemic hyperparathyroidism.

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