Senbanjo Richard, Strang John
East Kent Drug and Alcohol Recovery Service, Turning Point, Ashford, UK.
Eur Addict Res. 2015;21(4):204-10. doi: 10.1159/000375260. Epub 2015 Apr 21.
To assess the impact of femoral ultrasonography accompanied by explanation of the findings (UFV) on groin-injecting behaviour.
348 heroin-addicted groin injectors (GIs) on opioid substitution treatment (OST) were included in the study: 174 received UFV (cases), 174 did not (controls). Injecting behaviour among cases and matched controls were compared for both 'persistent GIs' (patients who had injected via the femoral vein in the 28-day period preceding the baseline) and 'former GIs' (patients with a history of previous groin injecting).
There were no significant between-group differences in gender, mean age, time in treatment, substitute medication and mean dose at baseline or injecting behaviour prior to baseline. After baseline, reduction by a third in the proportion still groin injecting was immediately evident among UFV cases versus controls (number needed to treat: 3, 95% CI: 2, 8; p < 0.001). Marked reduction in groin-injecting behaviour among UFV cases was maintained over 12 months, including fewer relapses among 'former GIs' (number needed to treat: 5, 95% CI: 4, 9; p < 0.001).
Single-session UFV may promote cessation of groin-injecting behaviour among patients receiving OST. This benefit appears to be evident 12 months later. Further evaluation of this novel approach to the management of groin injecting, a particularly harmful behaviour, is now warranted.
评估伴有检查结果解释的股部超声检查(UFV)对腹股沟注射行为的影响。
本研究纳入了348名接受阿片类药物替代治疗(OST)的海洛因成瘾腹股沟注射者(GI):174名接受了UFV(病例组),174名未接受(对照组)。比较了病例组和匹配对照组中“持续腹股沟注射者”(在基线前28天内通过股静脉注射的患者)和“既往腹股沟注射者”(有既往腹股沟注射史的患者)的注射行为。
在性别、平均年龄、治疗时间、替代药物以及基线时的平均剂量或基线前的注射行为方面,两组之间没有显著差异。基线后,与对照组相比,UFV病例组中仍进行腹股沟注射的比例立即下降了三分之一(治疗所需人数:3,95%置信区间:2,8;p<0.001)。UFV病例组中腹股沟注射行为的显著减少在12个月内持续存在,包括“既往腹股沟注射者”的复发减少(治疗所需人数:5,95%置信区间:4,9;p<0.001)。
单次UFV检查可能会促使接受OST的患者停止腹股沟注射行为。这种益处似乎在12个月后仍然明显。现在有必要对这种管理腹股沟注射(一种特别有害的行为)的新方法进行进一步评估。